Divergent synthesis and identification of the cellular targets of deoxyelephantopins
Deoxyelephantopin is a naturally occurring sesquiterpene lactone with known anticancer properties. Here, the authors synthesize deoxyelephantopins and a range of analogues including alkyne-tagged probes, using them to identify its cellular targets.
Main Authors: | Roman Lagoutte, Christelle Serba, Daniel Abegg, Dominic G. Hoch, Alexander Adibekian, Nicolas Winssinger |
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Format: | Article |
Language: | English |
Published: |
Nature Publishing Group
2016-08-01
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Series: | Nature Communications |
Online Access: | https://doi.org/10.1038/ncomms12470 |
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