Boron-mediated directed aromatic C–H hydroxylation
Transition metal-catalysed C–H hydroxylation is one of the most notable synthetic advances to access alcohols and phenols. Here, the authors report a metal-free, mild C–H hydroxylation of (hetero)arenes via boron-mediated chelation.
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Nature Publishing Group
2020-03-01
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Series: | Nature Communications |
Online Access: | https://doi.org/10.1038/s41467-020-15207-x |
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doaj-1ed1e283e9fb432eb928f81f9c819f252021-05-11T08:35:27ZengNature Publishing GroupNature Communications2041-17232020-03-011111810.1038/s41467-020-15207-xBoron-mediated directed aromatic C–H hydroxylationJiahang Lv0Binlin Zhao1Yu Yuan2Ying Han3Zhuangzhi Shi4State Key Laboratory of Coordination Chemistry, Chemistry and Biomedicine Innovation Center (ChemBIC), School of Chemistry and Chemical Engineering, Nanjing UniversityState Key Laboratory of Coordination Chemistry, Chemistry and Biomedicine Innovation Center (ChemBIC), School of Chemistry and Chemical Engineering, Nanjing UniversityCollege of Chemistry and Chemical Engineering, Yangzhou UniversityCollege of Chemistry and Chemical Engineering, Yangzhou UniversityState Key Laboratory of Coordination Chemistry, Chemistry and Biomedicine Innovation Center (ChemBIC), School of Chemistry and Chemical Engineering, Nanjing UniversityTransition metal-catalysed C–H hydroxylation is one of the most notable synthetic advances to access alcohols and phenols. Here, the authors report a metal-free, mild C–H hydroxylation of (hetero)arenes via boron-mediated chelation.https://doi.org/10.1038/s41467-020-15207-x |
collection |
DOAJ |
language |
English |
format |
Article |
sources |
DOAJ |
author |
Jiahang Lv Binlin Zhao Yu Yuan Ying Han Zhuangzhi Shi |
spellingShingle |
Jiahang Lv Binlin Zhao Yu Yuan Ying Han Zhuangzhi Shi Boron-mediated directed aromatic C–H hydroxylation Nature Communications |
author_facet |
Jiahang Lv Binlin Zhao Yu Yuan Ying Han Zhuangzhi Shi |
author_sort |
Jiahang Lv |
title |
Boron-mediated directed aromatic C–H hydroxylation |
title_short |
Boron-mediated directed aromatic C–H hydroxylation |
title_full |
Boron-mediated directed aromatic C–H hydroxylation |
title_fullStr |
Boron-mediated directed aromatic C–H hydroxylation |
title_full_unstemmed |
Boron-mediated directed aromatic C–H hydroxylation |
title_sort |
boron-mediated directed aromatic c–h hydroxylation |
publisher |
Nature Publishing Group |
series |
Nature Communications |
issn |
2041-1723 |
publishDate |
2020-03-01 |
description |
Transition metal-catalysed C–H hydroxylation is one of the most notable synthetic advances to access alcohols and phenols. Here, the authors report a metal-free, mild C–H hydroxylation of (hetero)arenes via boron-mediated chelation. |
url |
https://doi.org/10.1038/s41467-020-15207-x |
work_keys_str_mv |
AT jiahanglv boronmediateddirectedaromaticchhydroxylation AT binlinzhao boronmediateddirectedaromaticchhydroxylation AT yuyuan boronmediateddirectedaromaticchhydroxylation AT yinghan boronmediateddirectedaromaticchhydroxylation AT zhuangzhishi boronmediateddirectedaromaticchhydroxylation |
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1721450630820659200 |