Boron-mediated directed aromatic C–H hydroxylation

Transition metal-catalysed C–H hydroxylation is one of the most notable synthetic advances to access alcohols and phenols. Here, the authors report a metal-free, mild C–H hydroxylation of (hetero)arenes via boron-mediated chelation.

Bibliographic Details
Main Authors: Jiahang Lv, Binlin Zhao, Yu Yuan, Ying Han, Zhuangzhi Shi
Format: Article
Language:English
Published: Nature Publishing Group 2020-03-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-020-15207-x
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spelling doaj-1ed1e283e9fb432eb928f81f9c819f252021-05-11T08:35:27ZengNature Publishing GroupNature Communications2041-17232020-03-011111810.1038/s41467-020-15207-xBoron-mediated directed aromatic C–H hydroxylationJiahang Lv0Binlin Zhao1Yu Yuan2Ying Han3Zhuangzhi Shi4State Key Laboratory of Coordination Chemistry, Chemistry and Biomedicine Innovation Center (ChemBIC), School of Chemistry and Chemical Engineering, Nanjing UniversityState Key Laboratory of Coordination Chemistry, Chemistry and Biomedicine Innovation Center (ChemBIC), School of Chemistry and Chemical Engineering, Nanjing UniversityCollege of Chemistry and Chemical Engineering, Yangzhou UniversityCollege of Chemistry and Chemical Engineering, Yangzhou UniversityState Key Laboratory of Coordination Chemistry, Chemistry and Biomedicine Innovation Center (ChemBIC), School of Chemistry and Chemical Engineering, Nanjing UniversityTransition metal-catalysed C–H hydroxylation is one of the most notable synthetic advances to access alcohols and phenols. Here, the authors report a metal-free, mild C–H hydroxylation of (hetero)arenes via boron-mediated chelation.https://doi.org/10.1038/s41467-020-15207-x
collection DOAJ
language English
format Article
sources DOAJ
author Jiahang Lv
Binlin Zhao
Yu Yuan
Ying Han
Zhuangzhi Shi
spellingShingle Jiahang Lv
Binlin Zhao
Yu Yuan
Ying Han
Zhuangzhi Shi
Boron-mediated directed aromatic C–H hydroxylation
Nature Communications
author_facet Jiahang Lv
Binlin Zhao
Yu Yuan
Ying Han
Zhuangzhi Shi
author_sort Jiahang Lv
title Boron-mediated directed aromatic C–H hydroxylation
title_short Boron-mediated directed aromatic C–H hydroxylation
title_full Boron-mediated directed aromatic C–H hydroxylation
title_fullStr Boron-mediated directed aromatic C–H hydroxylation
title_full_unstemmed Boron-mediated directed aromatic C–H hydroxylation
title_sort boron-mediated directed aromatic c–h hydroxylation
publisher Nature Publishing Group
series Nature Communications
issn 2041-1723
publishDate 2020-03-01
description Transition metal-catalysed C–H hydroxylation is one of the most notable synthetic advances to access alcohols and phenols. Here, the authors report a metal-free, mild C–H hydroxylation of (hetero)arenes via boron-mediated chelation.
url https://doi.org/10.1038/s41467-020-15207-x
work_keys_str_mv AT jiahanglv boronmediateddirectedaromaticchhydroxylation
AT binlinzhao boronmediateddirectedaromaticchhydroxylation
AT yuyuan boronmediateddirectedaromaticchhydroxylation
AT yinghan boronmediateddirectedaromaticchhydroxylation
AT zhuangzhishi boronmediateddirectedaromaticchhydroxylation
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