Boron-mediated directed aromatic C–H hydroxylation

Transition metal-catalysed C–H hydroxylation is one of the most notable synthetic advances to access alcohols and phenols. Here, the authors report a metal-free, mild C–H hydroxylation of (hetero)arenes via boron-mediated chelation.

Bibliographic Details
Main Authors: Jiahang Lv, Binlin Zhao, Yu Yuan, Ying Han, Zhuangzhi Shi
Format: Article
Language:English
Published: Nature Publishing Group 2020-03-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-020-15207-x
Description
Summary:Transition metal-catalysed C–H hydroxylation is one of the most notable synthetic advances to access alcohols and phenols. Here, the authors report a metal-free, mild C–H hydroxylation of (hetero)arenes via boron-mediated chelation.
ISSN:2041-1723