Cell-Based Reporter Release Assay to Determine the Activity of Calcium-Dependent Neurotoxins and Neuroactive Pharmaceuticals
The suitability of a newly developed cell-based functional assay was tested for the detection of the activity of a range of neurotoxins and neuroactive pharmaceuticals which act by stimulation or inhibition of calcium-dependent neurotransmitter release. In this functional assay, a reporter enzyme is...
Main Authors: | Andrea Pathe-Neuschäfer-Rube, Frank Neuschäfer-Rube, Gerhard P. Püschel |
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Format: | Article |
Language: | English |
Published: |
MDPI AG
2021-03-01
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Series: | Toxins |
Subjects: | |
Online Access: | https://www.mdpi.com/2072-6651/13/4/247 |
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