Role of GRE imaging in cerebral diseases with hemorrhage: A case series

• Main Authors: Kamini Gupta, Puneet Mittal, Ranjana Gupta, Archana Ahluwalia
• Format: Article
• Language: English
• Published: Wolters Kluwer Medknow Publications 2014-01-01
• Series: Journal of Mahatma Gandhi Institute of Medical Sciences
• Subjects: Echo; gradient; hemorrhage; MRI
• Online Access: http://www.jmgims.co.in/article.asp?issn=0971-9903;year=2014;volume=19;issue=2;spage=159;epage=163;aulast=Gupta

Gradient recalled echo (GRE) T2 weighted imaging is more widely used as a standard magnetic resonance (MR) pulse sequence because of its exquisite sensitivity for detection of cerebral hemorrhages. Signal loss on GRE sequence is due to increased sensitivity of this sequence to magnetic susceptibility induced by static field inhomogeneities arising from paramagnetic blood breakdown products. T2 FNx01 signal intensity loss seen in GRE sequence is greater with longer TE, smaller flip angle, and larger magnetic field strength. The purpose of this review is to discuss the role of GRE imaging in cerebral disorders with bleed. Because of the sensitivity of this sequence to microbleeds, we describe its edge over baseline imaging sequences to provide insight in the etiology of certain diseases.