MicroRNA-Attenuated Virus Vaccines

Live-attenuated vaccines are the most effective way to establish robust, long-lasting immunity against viruses. However, the possibility of reversion to wild type replication and pathogenicity raises concerns over the safety of these vaccines. The use of host-derived microRNAs (miRNAs) to attenuate...

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Bibliographic Details
Main Authors: Elizabeth J. Fay, Ryan A. Langlois
Format: Article
Language:English
Published: MDPI AG 2018-10-01
Series:Non-Coding RNA
Subjects:
Online Access:http://www.mdpi.com/2311-553X/4/4/25

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