Developmental Programming in Response to Intrauterine Growth Restriction Impairs Myoblast Function and Skeletal Muscle Metabolism
Fetal adaptations to placental insufficiency alter postnatal metabolic homeostasis in skeletal muscle by reducing glucose oxidation rates, impairing insulin action, and lowering the proportion of oxidative fibers. In animal models of intrauterine growth restriction (IUGR), skeletal muscle fibers hav...
Main Authors: | D. T. Yates, A. R. Macko, M. Nearing, X. Chen, R. P. Rhoads, S. W. Limesand |
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Format: | Article |
Language: | English |
Published: |
Hindawi Limited
2012-01-01
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Series: | Journal of Pregnancy |
Online Access: | http://dx.doi.org/10.1155/2012/631038 |
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