LmSmdB: an integrated database for metabolic and gene regulatory network in Leishmania major and Schistosoma mansoni

• Main Authors: Priyanka Patel, Vineetha Mandlik, Shailza Singh
• Format: Article
• Language: English
• Published: Elsevier 2016-03-01
• Series: Genomics Data
• Online Access: http://www.sciencedirect.com/science/article/pii/S2213596015301124

A database that integrates all the information required for biological processing is essential to be stored in one platform. We have attempted to create one such integrated database that can be a one stop shop for the essential features required to fetch valuable result. LmSmdB (L. major and S. mansoni database) is an integrated database that accounts for the biological networks and regulatory pathways computationally determined by integrating the knowledge of the genome sequences of the mentioned organisms. It is the first database of its kind that has together with the network designing showed the simulation pattern of the product. This database intends to create a comprehensive canopy for the regulation of lipid metabolism reaction in the parasite by integrating the transcription factors, regulatory genes and the protein products controlled by the transcription factors and hence operating the metabolism at genetic level. Keywords: L.major, S.mansoni, Regulatory networks, Transcription factors, Database