Toxicity in hematopoietic stem cells from bone marrow and peripheral blood in mice after benzene exposure: Single-cell transcriptome sequencing analysis

Toxicity in hematopoietic stem cells from bone marrow and peripheral blood in mice after benzene exposure: Single-cell transcriptome sequencing analysis

Benzene is a ubiquitous, occupational, and environmental hematotoxic and leukemogen. Damage to hematopoietic stem cells (HSCs) induced by benzene and its metabolites is a key event in bone marrow (BM) depression and leukemogenesis. There are no reports on transcriptome profiles of HSCs following ben...

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Bibliographic Details
Main Authors: Rongli Sun, Kai Xu, Shuangbin Ji, Yunqiu Pu, Linling Yu, Lihong Yin, Juan Zhang, Yuepu Pu
Format: Article
Language:English
Published: Elsevier 2021-01-01
Series:Ecotoxicology and Environmental Safety
Subjects:
Benzene
Toxicity
Hematopoietic stem cell
Peripheral blood stem cell
Single cell transcriptome sequencing
Online Access:http://www.sciencedirect.com/science/article/pii/S0147651320313270

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