The combined fixed-dose antituberculous drugs alter some reproductive functions with oxidative stress involvement in wistar rats

The reproductive toxicity of combined fixed-dose first-line antituberculosis (CFDAT) regimen was assessed in rats. Thirty-two (32) Wistar rats weighing 168.1 ± 8.0 g were divided into four groups of eight rats per group. Two groups of male and female rats were administered oral distilled water (1.6 ...

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Bibliographic Details
Main Authors: O. Awodele, B.Pharm M.Sc MPH PhD D.Sc FPCPharm FASI, A.A. Momoh, N.A. Awolola, O.E. Kale, W.O. Okunowo
Format: Article
Language:English
Published: Elsevier 2016-01-01
Series:Toxicology Reports
Online Access:http://www.sciencedirect.com/science/article/pii/S221475001630049X