Complementing the sugar code: role of GAGs and sialic acid in complement regulation

Sugar molecules play a vital role on both microbial and mammalian cells, where they are involved in cellular communication, govern microbial virulence and modulate host immunity and inflammatory responses. The complement cascade, as part of a host’s innate immune system, is a potent weapon against i...

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Bibliographic Details
Main Authors: Alex eLangford-Smith, Anthony John Day, Paul Nicholas Bishop, Simon John Clark
Format: Article
Language:English
Published: Frontiers Media S.A. 2015-02-01
Series:Frontiers in Immunology
Subjects:
Online Access:http://journal.frontiersin.org/Journal/10.3389/fimmu.2015.00025/full