The Organ Handling of Soluble Klotho in Humans

The Organ Handling of Soluble Klotho in Humans

Background: Chronic kidney disease (CKD) reduces both Klotho expression and its shedding into circulation, an effect that accelerates progression and cardiovascular complications. However, the mechanisms that regulate Klotho release by the human kidney are still unknown. Methods: We measured plasma...

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Bibliographic Details
Main Authors: Daniela Picciotto, Abitha Murugavel, Francesca Ansaldo, Gian Marco Rosa, Antonella Sofia, Samantha Milanesi, Francesca Viazzi, Michela Saio, Manrico Balbi, Giacomo Garibotto, Daniela Verzola
Format: Article
Language:English
Published: Karger Publishers 2019-08-01
Series:Kidney & Blood Pressure Research
Subjects:
Klotho
Phosphate
Chronic kidney disease
Hypoxia
Online Access:https://www.karger.com/Article/FullText/501316

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