68Ga-Based Radiopharmaceuticals: Production and Application Relationship

The contribution of 68Ga to the promotion and expansion of clinical research and routine positron emission tomography (PET) for earlier better diagnostics and individualized medicine is considerable. The potential applications of 68Ga-comprising imaging agents include targeted, pre-targeted and non-...

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Bibliographic Details
Main Author: Irina Velikyan
Format: Article
Language:English
Published: MDPI AG 2015-07-01
Series:Molecules
Subjects:
GMP
Online Access:http://www.mdpi.com/1420-3049/20/7/12913
Description
Summary:The contribution of 68Ga to the promotion and expansion of clinical research and routine positron emission tomography (PET) for earlier better diagnostics and individualized medicine is considerable. The potential applications of 68Ga-comprising imaging agents include targeted, pre-targeted and non-targeted imaging. This review discusses the key aspects of the production of 68Ga and 68Ga-based radiopharmaceuticals in the light of the impact of regulatory requirements and endpoint pre-clinical and clinical applications.
ISSN:1420-3049