The soybean bioactive peptide VHVV alleviates hypertension-induced renal damage in hypertensive rats via the SIRT1-PGC1α/Nrf2 pathway

The soybean bioactive peptide VHVV alleviates hypertension-induced renal damage in hypertensive rats via the SIRT1-PGC1α/Nrf2 pathway

Hypertension triggers oxidative stress, causing dysfunction in organs, including the brain, heart, and kidney. In this study, we examined the potential renal benefit of the soybean bioactive peptide VHVV by in silico analysis and in spontaneously hypertensive rats. Sixteen-week-old spontaneously hyp...

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Bibliographic Details
Main Authors: Bruce Chi-Kang Tsai, Wei-Wen Kuo, Cecilia Hsuan Day, Dennis Jine-Yuan Hsieh, Chia-Hua Kuo, Jayasimharayalu Daddam, Ray-Jade Chen, V. Vijaya Padma, Guiqing Wang, Chih-Yang Huang
Format: Article
Language:English
Published: Elsevier 2020-12-01
Series:Journal of Functional Foods
Subjects:
Hypertension
Kidney
Soybean peptide
SIRT1
PGC1α
Nrf2
Online Access:http://www.sciencedirect.com/science/article/pii/S1756464620304795

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http://www.sciencedirect.com/science/article/pii/S1756464620304795

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