Ocrelizumab-Induced Severe Colitis

Ocrelizumab-Induced Severe Colitis

We report a case of severe ocrelizumab (anti-CD20 monoclonal antibody) induced colitis in a 43-year-old woman with multiple sclerosis leading to total colectomy after failing medical therapy. Histology of the colectomy was consistent with medication-induced colitis.

Bibliographic Details
Main Authors: Hsing Hwa Lee, Naveen Sritharan, Daniel Bermingham, Gabriela Strey
Format: Article
Language:English
Published: Hindawi Limited 2020-01-01
Series:Case Reports in Gastrointestinal Medicine
Online Access:http://dx.doi.org/10.1155/2020/8858378
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spelling doaj-1e8178303b9d461ba2e1816a10d3f0812020-12-21T11:41:29ZengHindawi LimitedCase Reports in Gastrointestinal Medicine2090-65282090-65362020-01-01202010.1155/2020/88583788858378Ocrelizumab-Induced Severe ColitisHsing Hwa Lee0Naveen Sritharan1Daniel Bermingham2Gabriela Strey3Department of Medicine, Hervey Bay Hospital, Pialba, Queensland, AustraliaDepartment of Medicine, Hervey Bay Hospital, Pialba, Queensland, AustraliaDepartment of Pharmacy, Hervey Bay Hospital, Pialba, Queensland, AustraliaDepartment of Medicine, Hervey Bay Hospital, Pialba, Queensland, AustraliaWe report a case of severe ocrelizumab (anti-CD20 monoclonal antibody) induced colitis in a 43-year-old woman with multiple sclerosis leading to total colectomy after failing medical therapy. Histology of the colectomy was consistent with medication-induced colitis.http://dx.doi.org/10.1155/2020/8858378
collection DOAJ
language English
format Article
sources DOAJ
author Hsing Hwa Lee
Naveen Sritharan
Daniel Bermingham
Gabriela Strey
spellingShingle Hsing Hwa Lee
Naveen Sritharan
Daniel Bermingham
Gabriela Strey
Ocrelizumab-Induced Severe Colitis
Case Reports in Gastrointestinal Medicine
author_facet Hsing Hwa Lee
Naveen Sritharan
Daniel Bermingham
Gabriela Strey
author_sort Hsing Hwa Lee
title Ocrelizumab-Induced Severe Colitis
title_short Ocrelizumab-Induced Severe Colitis
title_full Ocrelizumab-Induced Severe Colitis
title_fullStr Ocrelizumab-Induced Severe Colitis
title_full_unstemmed Ocrelizumab-Induced Severe Colitis
title_sort ocrelizumab-induced severe colitis
publisher Hindawi Limited
series Case Reports in Gastrointestinal Medicine
issn 2090-6528
2090-6536
publishDate 2020-01-01
description We report a case of severe ocrelizumab (anti-CD20 monoclonal antibody) induced colitis in a 43-year-old woman with multiple sclerosis leading to total colectomy after failing medical therapy. Histology of the colectomy was consistent with medication-induced colitis.
url http://dx.doi.org/10.1155/2020/8858378
work_keys_str_mv AT hsinghwalee ocrelizumabinducedseverecolitis
AT naveensritharan ocrelizumabinducedseverecolitis
AT danielbermingham ocrelizumabinducedseverecolitis
AT gabrielastrey ocrelizumabinducedseverecolitis
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