Targeting Synaptic Plasticity in Experimental Models of Alzheimer’s Disease

Targeting Synaptic Plasticity in Experimental Models of Alzheimer’s Disease

Long-term potentiation (LTP) and long-term depression (LTD) of hippocampal synaptic transmission represent the principal experimental models underlying learning and memory. Alterations of synaptic plasticity are observed in several neurodegenerative disorders, including Alzheimer’s disease (AD). Ind...

Full description

Bibliographic Details
Main Authors:	Dalila Mango, Amira Saidi, Giusy Ylenia Cisale, Marco Feligioni, Massimo Corbo, Robert Nisticò
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2019-07-01
Series:	Frontiers in Pharmacology
Subjects:	long-term potentiation long-term depression synaptic plasticity Alzheimer’s disease predictive validity
Online Access:	https://www.frontiersin.org/article/10.3389/fphar.2019.00778/full

Similar Items

Targeting Microglia-Synapse Interactions in Alzheimer’s Disease
by: Gaia Piccioni, et al.
Published: (2021-02-01)

The role of neuronal calcium sensors in balancing synaptic plasticity and synaptic dysfunction
by: Talitha Lynn Kerrigan, et al.
Published: (2012-05-01)

Convergent evidence for abnormal striatal synaptic plasticity in dystonia
by: David A. Peterson, et al.
Published: (2010-03-01)

Bidirectional Synaptic Plasticity Is Driven by Sex Neurosteroids Targeting Estrogen and Androgen Receptors in Hippocampal CA1 Pyramidal Neurons
by: Alessandro Tozzi, et al.
Published: (2019-12-01)

Diacylglycerol kinases in the coordination of synaptic plasticity
by: Dongwon Lee, et al.
Published: (2016-08-01)

The role of astrocytic aquaporin-4 in synaptic plasticity and learning and memory
by: Jenny I. Szu, et al.
Published: (2016-02-01)

Trigonelline Ameliorates Learning and Memory and Synaptic Plasticity Impairment in Intrahippocampal Amyloid Beta (1-40) Rat Model of Alzheimer’s Disease
by: Javad Fahanik-Babaei, et al.
Published: (2019-01-01)

Selective role of the translin/trax RNase complex in hippocampal synaptic plasticity
by: Alan Jung Park, et al.
Published: (2020-11-01)

Decoding the synaptic dysfunction of bioactive human AD brain soluble Aβ to inspire novel therapeutic avenues for Alzheimer’s disease
by: Shaomin Li, et al.
Published: (2018-11-01)

Long-term plasticity determines the postsynaptic response to correlated afferents with multivesicular short-term synaptic depression
by: Alexander David Bird, et al.
Published: (2014-01-01)

Chronic Sodium Selenate Treatment Restores Deficits in Cognition and Synaptic Plasticity in a Murine Model of Tauopathy
by: Tariq Ahmed, et al.
Published: (2020-10-01)

A transgenic rat that develops Alzheimer's disease-like amyloid pathology, deficits in synaptic plasticity and cognitive impairment
by: Li Liu, et al.
Published: (2008-07-01)

Presynaptic long-term plasticity
by: Ying eYang, et al.
Published: (2013-10-01)

Corrigendum: Dynamic expression of long noncoding RNAs and repeat elements in synaptic plasticity
by: Jesper Lars Viktor Maag, et al.
Published: (2016-07-01)

Soluble prion protein and its N-terminal fragment prevent impairment of synaptic plasticity by Aβ oligomers: Implications for novel therapeutic strategy in Alzheimer's disease
by: Jonah J. Scott-McKean, et al.
Published: (2016-07-01)

P2Y1 receptor inhibition rescues impaired synaptic plasticity and astroglial Ca2+-dependent activity in the epileptic hippocampus
by: Andrés Martorell, et al.
Published: (2020-12-01)

Spike timing dependent plasticity: a consequence of more fundamental learning rules
by: Harel Z Shouval, et al.
Published: (2010-07-01)

Doxorubicin induces dysregulation of AMPA receptor and impairs hippocampal synaptic plasticity leading to learning and memory deficits
by: Ahmad H. Alhowail, et al.
Published: (2021-07-01)

Glutamate receptor delocalization in postsynaptic membrane and reduced hippocampal synaptic plasticity in the early stage of Alzheimer’s disease
by: Ning Li, et al.
Published: (2019-01-01)

A Practical Guide to Using CV Analysis for Determining the Locus of Synaptic Plasticity
by: Jennifer A. Brock, et al.
Published: (2020-03-01)

The role of nitric oxide in pre-synaptic plasticity and homeostasis
by: Neil eHardingham, et al.
Published: (2013-10-01)

The Onset and Progression of Hippocampal Synaptic Plasticity Deficits in the Q175FDN Mouse Model of Huntington Disease
by: Jade G. Quirion, et al.
Published: (2019-07-01)

Learning-facilitated synaptic plasticity occurs in the intermediate hippocampus in association with spatial learning
by: Jana eKenney, et al.
Published: (2013-10-01)

The epitranscriptome in modulating spatiotemporal RNA translation in neuronal post-synaptic function
by: Shobbir eHussain, et al.
Published: (2015-10-01)

Effect of Aggregated β-Amyloid (1-42) on Synaptic Plasticity of Hippocampal Dentate Gyrus Granule Cells in Vivo
by: Shirin Babri, et al.
Published: (2012-12-01)

A history of spike-timing-dependent plasticity
by: Henry eMarkram, et al.
Published: (2011-08-01)

Self-organized reactivation maintains and reinforces memories despite synaptic turnover
by: Michael Jan Fauth, et al.
Published: (2019-05-01)

mGluR-dependent synaptic plasticity in drug-seeking.
by: Camilla eBellone, et al.
Published: (2012-08-01)

Normal induction but accelerated decay of LTP in APP + PS1 transgenic mice
by: I Gureviciene, et al.
Published: (2004-03-01)

Physiology of Cerebellar Reserve: Redundancy and Plasticity of a Modular Machine
by: Hiroshi Mitoma, et al.
Published: (2021-04-01)

Facemasks and face recognition: Potential impact on synaptic plasticity
by: Chiara Ferrari, et al.
Published: (2021-06-01)

The demise of the synapse as the locus of memory: A looming paradigm shift?
by: Patrick C. Trettenbrein, et al.
Published: (2016-11-01)

Plasticity-related microRNA and their potential contribution to the maintenance of long-term potentiation
by: Brigid eRyan, et al.
Published: (2015-02-01)

Alzheimer’s disease Aβ assemblies mediating rapid disruption of synaptic plasticity and memory
by: Klyubin Igor, et al.
Published: (2012-07-01)

Plasticity resembling spike-timing dependent synaptic plasticity: the evidence in human cortex
by: Florian Müller-Dahlhaus, et al.
Published: (2010-07-01)

Suppression of synaptic plasticity by cerebrospinal fluid from anti-NMDA receptor encephalitis patients
by: Qing Zhang, et al.
Published: (2012-01-01)

Storing and retrieving long-term memories: cooperation and competition in synaptic dynamics
by: Anita Mehta
Published: (2018-01-01)

Commentary Reinstatement of long-term memory following erasure of its behavioral and synaptic expression in Aplysia
by: Patrick C. Trettenbrein, et al.
Published: (2015-08-01)

INTERMOLECULAR INTERACTIONS IN NEURONAL FUNCTIONAL SYSTEMS
by: A. L. Proskura, et al.
Published: (2015-01-01)

Synaptic impairment in layer 1 of the prefrontal cortex induced by repeated stress during adolescence is reversed in adulthood
by: Ignacio eNegron-Oyarzo, et al.
Published: (2015-11-01)

Cannot write session to /tmp/vufind_sessions/sess_r6tulitr9hpp7q315aqjt791ss