Epigenetic mechanisms involved in differential <it>MDR1 </it>mRNA expression between gastric and colon cancer cell lines and rationales for clinical chemotherapy

<p>Abstract</p> <p>Background</p> <p>The membrane transporters such as P-glycoprotein (Pgp), the <it>MDR1 </it>gene product, are one of causes of treatment failure in cancer patients. In this study, the epigenetic mechanisms involved in differential <it&g...

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Bibliographic Details
Main Authors: Kim Kyung-Jong, Min Young-Don, Park Jung-Hee, Lee Tae-Bum, Choi Cheol-Hee
Format: Article
Language:English
Published: BMC 2008-08-01
Series:BMC Gastroenterology
Online Access:http://www.biomedcentral.com/1471-230X/8/33