Sea squirt alternative oxidase bypasses fatal mitochondrial heart disease

Mitochondrial diseases are a diverse group of inborn disorders affecting cellular energy production by oxidative phosphorylation (OXPHOS) via the five (CI‐CV) mitochondrial respiratory chain (MRC) complexes. The sea squirt alternative oxidase (AOX) is able to bypass the distal part of the MRC and wa...

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Bibliographic Details
Main Author: Ann Saada
Format: Article
Language:English
Published: Wiley 2019-01-01
Series:EMBO Molecular Medicine
Online Access:https://doi.org/10.15252/emmm.201809962