Determinants of uncontrolled hypertension in adult type 2 diabetes mellitus: an analysis of the Malaysian diabetes registry 2009

<p>Abstract</p> <p>Background</p> <p>Uncontrolled blood pressure (BP) is a significant contributor of morbidity and even mortality in type 2 diabetes (T2D) patients. This study was done to determine the significant determinants of uncontrolled blood pressure in T2D pati...

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Main Authors: Chew Boon How, Mastura Ismail, Shariff-Ghazali Sazlina, Lee Ping Yein, Cheong Ai Theng, Ahmad Zaiton, Taher Sri, Haniff Jamaiyah, Mustapha Feisul, Bujang Mohd
Format: Article
Language:English
Published: BMC 2012-05-01
Series:Cardiovascular Diabetology
Subjects:
Online Access:http://www.cardiab.com/content/11/1/54
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spelling doaj-1e5f1748add64627a62d7830a3935bd42020-11-25T01:29:47ZengBMCCardiovascular Diabetology1475-28402012-05-011115410.1186/1475-2840-11-54Determinants of uncontrolled hypertension in adult type 2 diabetes mellitus: an analysis of the Malaysian diabetes registry 2009Chew Boon HowMastura IsmailShariff-Ghazali SazlinaLee Ping YeinCheong Ai ThengAhmad ZaitonTaher SriHaniff JamaiyahMustapha FeisulBujang Mohd<p>Abstract</p> <p>Background</p> <p>Uncontrolled blood pressure (BP) is a significant contributor of morbidity and even mortality in type 2 diabetes (T2D) patients. This study was done to determine the significant determinants of uncontrolled blood pressure in T2D patients in Malaysia.</p> <p>Methods</p> <p>Between 1<sup>st</sup> January 2009 to 31<sup>st</sup> December 2009, data from 70 889 patients with Type 2 diabetes was obtained from the Adult Diabetes Control and Management Registry for analysis; 303 centers participated in the study. Their demographic characteristics, the nature of their diabetes, their state of hypertension, treatment modalities, risk factors, and complications are described. Based on their most recent BP values, subjects were divided into controlled BP and uncontrolled BP and their clinical determinants compared. Independent determinants were identified using multivariate logistic regression.</p> <p>Results</p> <p>The mean age of patients at diagnosis of diabetes was 52.3 ± 11.1 years old. Most were women (59.0 %) and of Malay ethnicity (61.9 %). The mean duration of diabetes was 5.9 ± 5.6 years. A total of 57.4 % were hypertensive. Of the 56 503 blood pressure (BP) measured, 13 280 (23.5 %) patients had BP <130/80 mmHg. Eighteen percent was on > two anti-hypertensive agents. Health clinics without doctor, older age (≥ 50 years old), shorter duration of diabetes (< 5 years), Malay, overweight were determinants for uncontrolled blood pressure (BP ≥130/80 mmHg). Patients who were on anti-hypertensive agent/s were 2.7 times more likely to have BP ≥130/80 mmHg. Type 2 diabetes patients who had ischaemic heart disease or nephropathy were about 20 % and 15 % more likely to have their blood pressure treated to target respectively.</p> <p>Conclusions</p> <p>Major independent determinants of uncontrolled BP in our group of T2D patients were Malay ethnicity, older age, recent diagnosis of diabetes, overweight and follow-up at health clinics without a doctor and possibly the improper use of anti hypertensive agent. More effort, education and resources, especially in the primary health care centres are needed to improve hypertensive care among our patients with diabetes.</p> http://www.cardiab.com/content/11/1/54Type 2 Diabetes MellitusHypertensionAntihypertensive agentsPrimary care
collection DOAJ
language English
format Article
sources DOAJ
author Chew Boon How
Mastura Ismail
Shariff-Ghazali Sazlina
Lee Ping Yein
Cheong Ai Theng
Ahmad Zaiton
Taher Sri
Haniff Jamaiyah
Mustapha Feisul
Bujang Mohd
spellingShingle Chew Boon How
Mastura Ismail
Shariff-Ghazali Sazlina
Lee Ping Yein
Cheong Ai Theng
Ahmad Zaiton
Taher Sri
Haniff Jamaiyah
Mustapha Feisul
Bujang Mohd
Determinants of uncontrolled hypertension in adult type 2 diabetes mellitus: an analysis of the Malaysian diabetes registry 2009
Cardiovascular Diabetology
Type 2 Diabetes Mellitus
Hypertension
Antihypertensive agents
Primary care
author_facet Chew Boon How
Mastura Ismail
Shariff-Ghazali Sazlina
Lee Ping Yein
Cheong Ai Theng
Ahmad Zaiton
Taher Sri
Haniff Jamaiyah
Mustapha Feisul
Bujang Mohd
author_sort Chew Boon How
title Determinants of uncontrolled hypertension in adult type 2 diabetes mellitus: an analysis of the Malaysian diabetes registry 2009
title_short Determinants of uncontrolled hypertension in adult type 2 diabetes mellitus: an analysis of the Malaysian diabetes registry 2009
title_full Determinants of uncontrolled hypertension in adult type 2 diabetes mellitus: an analysis of the Malaysian diabetes registry 2009
title_fullStr Determinants of uncontrolled hypertension in adult type 2 diabetes mellitus: an analysis of the Malaysian diabetes registry 2009
title_full_unstemmed Determinants of uncontrolled hypertension in adult type 2 diabetes mellitus: an analysis of the Malaysian diabetes registry 2009
title_sort determinants of uncontrolled hypertension in adult type 2 diabetes mellitus: an analysis of the malaysian diabetes registry 2009
publisher BMC
series Cardiovascular Diabetology
issn 1475-2840
publishDate 2012-05-01
description <p>Abstract</p> <p>Background</p> <p>Uncontrolled blood pressure (BP) is a significant contributor of morbidity and even mortality in type 2 diabetes (T2D) patients. This study was done to determine the significant determinants of uncontrolled blood pressure in T2D patients in Malaysia.</p> <p>Methods</p> <p>Between 1<sup>st</sup> January 2009 to 31<sup>st</sup> December 2009, data from 70 889 patients with Type 2 diabetes was obtained from the Adult Diabetes Control and Management Registry for analysis; 303 centers participated in the study. Their demographic characteristics, the nature of their diabetes, their state of hypertension, treatment modalities, risk factors, and complications are described. Based on their most recent BP values, subjects were divided into controlled BP and uncontrolled BP and their clinical determinants compared. Independent determinants were identified using multivariate logistic regression.</p> <p>Results</p> <p>The mean age of patients at diagnosis of diabetes was 52.3 ± 11.1 years old. Most were women (59.0 %) and of Malay ethnicity (61.9 %). The mean duration of diabetes was 5.9 ± 5.6 years. A total of 57.4 % were hypertensive. Of the 56 503 blood pressure (BP) measured, 13 280 (23.5 %) patients had BP <130/80 mmHg. Eighteen percent was on > two anti-hypertensive agents. Health clinics without doctor, older age (≥ 50 years old), shorter duration of diabetes (< 5 years), Malay, overweight were determinants for uncontrolled blood pressure (BP ≥130/80 mmHg). Patients who were on anti-hypertensive agent/s were 2.7 times more likely to have BP ≥130/80 mmHg. Type 2 diabetes patients who had ischaemic heart disease or nephropathy were about 20 % and 15 % more likely to have their blood pressure treated to target respectively.</p> <p>Conclusions</p> <p>Major independent determinants of uncontrolled BP in our group of T2D patients were Malay ethnicity, older age, recent diagnosis of diabetes, overweight and follow-up at health clinics without a doctor and possibly the improper use of anti hypertensive agent. More effort, education and resources, especially in the primary health care centres are needed to improve hypertensive care among our patients with diabetes.</p>
topic Type 2 Diabetes Mellitus
Hypertension
Antihypertensive agents
Primary care
url http://www.cardiab.com/content/11/1/54
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