Erlotinib hydrochloride: an anticancer agent

Erlotinib hydrochloride: an anticancer agent

In the cation of the title compound, C22H24N3O4+·Cl−, an active ingredient of the anticancer drug also known as Tarceva, the quinazoline ring system is planar within 0.044 (3) Å. The dihedral angle formed by the mean planes of the two six-membered quin...

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Main Authors: K. Ravikumar, B. Sridhar, S. Selvanayagam
Format: Article
Language:English
Published: International Union of Crystallography 2008-05-01
Series:Acta Crystallographica Section E
Online Access:http://scripts.iucr.org/cgi-bin/paper?S1600536808011707
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spelling doaj-1e5a5f94233f467cb02025c8fb17455c2020-11-25T01:33:27ZengInternational Union of CrystallographyActa Crystallographica Section E1600-53682008-05-01645o931o93110.1107/S1600536808011707Erlotinib hydrochloride: an anticancer agentK. RavikumarB. SridharS. SelvanayagamIn the cation of the title compound, C22H24N3O4+·Cl−, an active ingredient of the anticancer drug also known as Tarceva, the quinazoline ring system is planar within 0.044 (3) Å. The dihedral angle formed by the mean planes of the two six-membered quinazoline rings is 3.2 (1)°. Both N-bound H atoms participate in N—H...Cl bonds, which link the ions into infinite chains running along the b axis. C—H...O interactions involving neighboring cations provide additional stabilization of these aggregates.http://scripts.iucr.org/cgi-bin/paper?S1600536808011707
collection DOAJ
language English
format Article
sources DOAJ
author K. Ravikumar
B. Sridhar
S. Selvanayagam
spellingShingle K. Ravikumar
B. Sridhar
S. Selvanayagam
Erlotinib hydrochloride: an anticancer agent
Acta Crystallographica Section E
author_facet K. Ravikumar
B. Sridhar
S. Selvanayagam
author_sort K. Ravikumar
title Erlotinib hydrochloride: an anticancer agent
title_short Erlotinib hydrochloride: an anticancer agent
title_full Erlotinib hydrochloride: an anticancer agent
title_fullStr Erlotinib hydrochloride: an anticancer agent
title_full_unstemmed Erlotinib hydrochloride: an anticancer agent
title_sort erlotinib hydrochloride: an anticancer agent
publisher International Union of Crystallography
series Acta Crystallographica Section E
issn 1600-5368
publishDate 2008-05-01
description In the cation of the title compound, C22H24N3O4+·Cl−, an active ingredient of the anticancer drug also known as Tarceva, the quinazoline ring system is planar within 0.044 (3) Å. The dihedral angle formed by the mean planes of the two six-membered quinazoline rings is 3.2 (1)°. Both N-bound H atoms participate in N—H...Cl bonds, which link the ions into infinite chains running along the b axis. C—H...O interactions involving neighboring cations provide additional stabilization of these aggregates.
url http://scripts.iucr.org/cgi-bin/paper?S1600536808011707
work_keys_str_mv AT kravikumar erlotinibhydrochlorideananticanceragent
AT bsridhar erlotinibhydrochlorideananticanceragent
AT sselvanayagam erlotinibhydrochlorideananticanceragent
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