| Summary: | Aim: The objective of this study is comparing the effects of
intra-articular hyaluronic acid (HA) and tenoxicam aplications on joint range
of motion (ROM) and pain in patients with gonarthrosis.Patients
and Method: This study was designed
as prospective, non-randomized controlled, and single-blinded trial. 60
patients diagnosed with Grade II and Grade III osteoarthritis (OA) according to
the American College of Rheumatology (ACR) criteria were consecutively
enrolled. Patients were divided into two groups whereby the first group
received intra-articular HA three times a week and the other group received a
single dose intra-articular tenoxicam. Pre-treatment and after-treatment VAS
and ROM values of the groups were compared.Results: In the HA Group, 20 patients (66.6%) were female, 10
patients (33.3%) were male and the mean age of them was 59.6 years (range 45-75
years). In the Tenoxicam Group, 24 patients (80%) were female, 6 (20%) patients
were male, and the average age of this group was 61.5 years (range 45-75
years). VAS scores knee flexion and extension ROM values on the 1st day, the
15th day, the 1st month,the2nd month, and the 3rd month after the treatment,
significantly improved in both groups (p <0.05). When the change levels in
the groups were compared, the changes in the Tenoxicam Group were more
prominent in the early period, but there was no difference between the two
groups in terms of the 3rd-month values after the treatment (p> 0.05).
Conclusion: It was seen that intra-articular HA and tenoxicam administration
seem to be effective and reliable methods in Grade 2-3 knee OA patients; but
tenoxicam was more effective in reducing pain and relieving joint movements
compared to HA injection in the early periods.
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