Impacts of Humanized Mouse Models on the Investigation of HIV-1 Infection: Illuminating the Roles of Viral Accessory Proteins in Vivo

Impacts of Humanized Mouse Models on the Investigation of HIV-1 Infection: Illuminating the Roles of Viral Accessory Proteins in Vivo

Human immunodeficiency virus type 1 (HIV-1) encodes four accessory genes: vif, vpu, vpr, and nef. Recent investigations using in vitro cell culture systems have shed light on the roles of these HIV-1 accessory proteins, Vif, Vpr, Vpu, and Nef, in counteracting, modulating, and evading various cellul...

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Bibliographic Details
Main Authors: Eri Yamada, Rokusuke Yoshikawa, Yusuke Nakano, Naoko Misawa, Yoshio Koyanagi, Kei Sato
Format: Article
Language:English
Published: MDPI AG 2015-03-01
Series:Viruses
Subjects:
HIV-1
accessory protein
humanized mouse model
Online Access:http://www.mdpi.com/1999-4915/7/3/1373

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http://www.mdpi.com/1999-4915/7/3/1373

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