Apoptosis inducing factor deficiency causes retinal photoreceptor degeneration. The protective role of the redox compound methylene blue
Dysfunction in mitochondrial oxidative phosphorylation (OXPHOS) underlies a wide spectrum of human ailments known as mitochondrial diseases. Deficiencies in complex I of the electron transport chain (ETC) contribute to 30–40% of all cases of mitochondrial diseases, and leads to eye disease including...
Main Authors: | Naveen K. Mekala, Jacob Kurdys, Mikayla M. Depuydt, Edwin J. Vazquez, Mariana G. Rosca |
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Format: | Article |
Language: | English |
Published: |
Elsevier
2019-01-01
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Series: | Redox Biology |
Online Access: | http://www.sciencedirect.com/science/article/pii/S2213231718307626 |
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