Data on hypoxia-induced VEGF, leptin and NF-kB p65 expression
The data set presented here is associated with the article “Intracellular calcium and NF-kB regulate hypoxia-induced leptin, VEGF, IL-6 and adiponectin secretion in human adipocytes” (Al-Anazi et al., 2018). Data illustrate hypoxia-induced VEGF and leptin expression in human adipocytes treated with...
| Main Authors: | , , , , , , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Elsevier
2018-12-01
|
| Series: | Data in Brief |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S2352340918313647 |
| id |
doaj-1e4d16d5a4824932b637fd1cdb373753 |
|---|---|
| record_format |
Article |
| spelling |
doaj-1e4d16d5a4824932b637fd1cdb3737532020-11-25T02:40:23ZengElsevierData in Brief2352-34092018-12-012123952397Data on hypoxia-induced VEGF, leptin and NF-kB p65 expressionAzizah Al-Anazi0Ranjit Parhar1Soad Saleh2Reem Al-Hijailan3Angela Inglis4Mansour Al-Jufan5Mohammed Bazzi6Sarwar Hashmi7Walter Conca8Kate Collison9Futwan Al-Mohanna10Department of Cell Biology, Riyadh 11211, Saudi ArabiaDepartment of Cell Biology, Riyadh 11211, Saudi ArabiaDepartment of Cell Biology, Riyadh 11211, Saudi ArabiaDepartment of Cell Biology, Riyadh 11211, Saudi ArabiaDepartment of Cell Biology, Riyadh 11211, Saudi ArabiaHeart Centre, King Faisal Specialist Hospital and Research Centre, Riyadh 11211, Saudi ArabiaDepartment of Biochemistry, College of Science, King Saud University, Riyadh 12372, Saudi ArabiaDevelopmental Biology, Center for Vector Biology, Rutgers University, New Brunswick, NJ 08901, United StatesDepartment of Cell Biology, Riyadh 11211, Saudi Arabia; Department of Medicine, King Faisal Specialist Hospital and Research Centre, Alfaisal University, Riyadh 11211, Saudi Arabia; College of Medicine, Alfaisal University, Riyadh 11211, Saudi ArabiaDepartment of Cell Biology, Riyadh 11211, Saudi ArabiaDepartment of Cell Biology, Riyadh 11211, Saudi Arabia; College of Medicine, Alfaisal University, Riyadh 11211, Saudi Arabia; Correspondence to: Department of Cell Biology, MBC 03, King Faisal Specialist Hospital and Research Centre, Riyadh 11211, Saudi Arabia.The data set presented here is associated with the article “Intracellular calcium and NF-kB regulate hypoxia-induced leptin, VEGF, IL-6 and adiponectin secretion in human adipocytes” (Al-Anazi et al., 2018). Data illustrate hypoxia-induced VEGF and leptin expression in human adipocytes treated with the calcium chelator BAPTA-AM (1 µM). It also shows NF-κB p65 induced expression by hypoxia. Preadipocytes were differentiated for 14 days and then subjected to 0.5–1.5% oxygen in the presence and absence of BAPTA-AM or the NF-κB inhibitor SN50 for 48 h prior to RNA isolation and PCR analysis.http://www.sciencedirect.com/science/article/pii/S2352340918313647 |
| collection |
DOAJ |
| language |
English |
| format |
Article |
| sources |
DOAJ |
| author |
Azizah Al-Anazi Ranjit Parhar Soad Saleh Reem Al-Hijailan Angela Inglis Mansour Al-Jufan Mohammed Bazzi Sarwar Hashmi Walter Conca Kate Collison Futwan Al-Mohanna |
| spellingShingle |
Azizah Al-Anazi Ranjit Parhar Soad Saleh Reem Al-Hijailan Angela Inglis Mansour Al-Jufan Mohammed Bazzi Sarwar Hashmi Walter Conca Kate Collison Futwan Al-Mohanna Data on hypoxia-induced VEGF, leptin and NF-kB p65 expression Data in Brief |
| author_facet |
Azizah Al-Anazi Ranjit Parhar Soad Saleh Reem Al-Hijailan Angela Inglis Mansour Al-Jufan Mohammed Bazzi Sarwar Hashmi Walter Conca Kate Collison Futwan Al-Mohanna |
| author_sort |
Azizah Al-Anazi |
| title |
Data on hypoxia-induced VEGF, leptin and NF-kB p65 expression |
| title_short |
Data on hypoxia-induced VEGF, leptin and NF-kB p65 expression |
| title_full |
Data on hypoxia-induced VEGF, leptin and NF-kB p65 expression |
| title_fullStr |
Data on hypoxia-induced VEGF, leptin and NF-kB p65 expression |
| title_full_unstemmed |
Data on hypoxia-induced VEGF, leptin and NF-kB p65 expression |
| title_sort |
data on hypoxia-induced vegf, leptin and nf-kb p65 expression |
| publisher |
Elsevier |
| series |
Data in Brief |
| issn |
2352-3409 |
| publishDate |
2018-12-01 |
| description |
The data set presented here is associated with the article “Intracellular calcium and NF-kB regulate hypoxia-induced leptin, VEGF, IL-6 and adiponectin secretion in human adipocytes” (Al-Anazi et al., 2018). Data illustrate hypoxia-induced VEGF and leptin expression in human adipocytes treated with the calcium chelator BAPTA-AM (1 µM). It also shows NF-κB p65 induced expression by hypoxia. Preadipocytes were differentiated for 14 days and then subjected to 0.5–1.5% oxygen in the presence and absence of BAPTA-AM or the NF-κB inhibitor SN50 for 48 h prior to RNA isolation and PCR analysis. |
| url |
http://www.sciencedirect.com/science/article/pii/S2352340918313647 |
| work_keys_str_mv |
AT azizahalanazi dataonhypoxiainducedvegfleptinandnfkbp65expression AT ranjitparhar dataonhypoxiainducedvegfleptinandnfkbp65expression AT soadsaleh dataonhypoxiainducedvegfleptinandnfkbp65expression AT reemalhijailan dataonhypoxiainducedvegfleptinandnfkbp65expression AT angelainglis dataonhypoxiainducedvegfleptinandnfkbp65expression AT mansouraljufan dataonhypoxiainducedvegfleptinandnfkbp65expression AT mohammedbazzi dataonhypoxiainducedvegfleptinandnfkbp65expression AT sarwarhashmi dataonhypoxiainducedvegfleptinandnfkbp65expression AT walterconca dataonhypoxiainducedvegfleptinandnfkbp65expression AT katecollison dataonhypoxiainducedvegfleptinandnfkbp65expression AT futwanalmohanna dataonhypoxiainducedvegfleptinandnfkbp65expression |
| _version_ |
1724782114354757632 |