Vitamin C and Cardiovascular Disease: An Update

The potential beneficial effects of the antioxidant properties of vitamin C have been investigated in a number of pathological conditions. In this review, we assess both clinical and preclinical studies evaluating the role of vitamin C in cardiac and vascular disorders, including coronary heart dise...

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Main Authors: Marco B. Morelli, Jessica Gambardella, Vanessa Castellanos, Valentina Trimarco, Gaetano Santulli
Format: Article
Language:English
Published: MDPI AG 2020-12-01
Series:Antioxidants
Subjects:
Online Access:https://www.mdpi.com/2076-3921/9/12/1227
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spelling doaj-1e31dc0e187e4a9184fcdf1c013279012020-12-04T00:06:23ZengMDPI AGAntioxidants2076-39212020-12-0191227122710.3390/antiox9121227Vitamin C and Cardiovascular Disease: An UpdateMarco B. Morelli0Jessica Gambardella1Vanessa Castellanos2Valentina Trimarco3Gaetano Santulli4Division of Cardiology, Department of Medicine, Institute of Aging Research, Wilf Family Cardiovascular Research Institute, Albert Einstein College of Medicine, Montefiore University Hospital, New York, NY 10461, USADivision of Cardiology, Department of Medicine, Institute of Aging Research, Wilf Family Cardiovascular Research Institute, Albert Einstein College of Medicine, Montefiore University Hospital, New York, NY 10461, USADivision of Cardiology, Department of Medicine, Institute of Aging Research, Wilf Family Cardiovascular Research Institute, Albert Einstein College of Medicine, Montefiore University Hospital, New York, NY 10461, USADepartment of Neuroscience, “Federico II” University, 80131 Naples, ItalyDivision of Cardiology, Department of Medicine, Institute of Aging Research, Wilf Family Cardiovascular Research Institute, Albert Einstein College of Medicine, Montefiore University Hospital, New York, NY 10461, USAThe potential beneficial effects of the antioxidant properties of vitamin C have been investigated in a number of pathological conditions. In this review, we assess both clinical and preclinical studies evaluating the role of vitamin C in cardiac and vascular disorders, including coronary heart disease, heart failure, hypertension, and cerebrovascular diseases. Pitfalls and controversies in investigations on vitamin C and cardiovascular disorders are also discussed.https://www.mdpi.com/2076-3921/9/12/1227ascorbic acidblood pressurecoronavirusCOVID–19dietary supplementsdrug formulations
collection DOAJ
language English
format Article
sources DOAJ
author Marco B. Morelli
Jessica Gambardella
Vanessa Castellanos
Valentina Trimarco
Gaetano Santulli
spellingShingle Marco B. Morelli
Jessica Gambardella
Vanessa Castellanos
Valentina Trimarco
Gaetano Santulli
Vitamin C and Cardiovascular Disease: An Update
Antioxidants
ascorbic acid
blood pressure
coronavirus
COVID–19
dietary supplements
drug formulations
author_facet Marco B. Morelli
Jessica Gambardella
Vanessa Castellanos
Valentina Trimarco
Gaetano Santulli
author_sort Marco B. Morelli
title Vitamin C and Cardiovascular Disease: An Update
title_short Vitamin C and Cardiovascular Disease: An Update
title_full Vitamin C and Cardiovascular Disease: An Update
title_fullStr Vitamin C and Cardiovascular Disease: An Update
title_full_unstemmed Vitamin C and Cardiovascular Disease: An Update
title_sort vitamin c and cardiovascular disease: an update
publisher MDPI AG
series Antioxidants
issn 2076-3921
publishDate 2020-12-01
description The potential beneficial effects of the antioxidant properties of vitamin C have been investigated in a number of pathological conditions. In this review, we assess both clinical and preclinical studies evaluating the role of vitamin C in cardiac and vascular disorders, including coronary heart disease, heart failure, hypertension, and cerebrovascular diseases. Pitfalls and controversies in investigations on vitamin C and cardiovascular disorders are also discussed.
topic ascorbic acid
blood pressure
coronavirus
COVID–19
dietary supplements
drug formulations
url https://www.mdpi.com/2076-3921/9/12/1227
work_keys_str_mv AT marcobmorelli vitamincandcardiovasculardiseaseanupdate
AT jessicagambardella vitamincandcardiovasculardiseaseanupdate
AT vanessacastellanos vitamincandcardiovasculardiseaseanupdate
AT valentinatrimarco vitamincandcardiovasculardiseaseanupdate
AT gaetanosantulli vitamincandcardiovasculardiseaseanupdate
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