Serum IgG antibody levels to periodontal microbiota are associated with incident Alzheimer disease.

Serum IgG antibody levels to periodontal microbiota are associated with incident Alzheimer disease.

Periodontitis and Alzheimer disease (AD) are associated with systemic inflammation. This research studied serum IgG to periodontal microbiota as possible predictors of incident AD.Using a case-cohort study design, 219 subjects (110 incident AD cases and 109 controls without incident cognitive impair...

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Bibliographic Details
Main Authors: James M Noble, Nikolaos Scarmeas, Romanita S Celenti, Mitchell S V Elkind, Clinton B Wright, Nicole Schupf, Panos N Papapanou
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4270775?pdf=render

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