Microwave Induced Synthesis and Anti bacterial Activity of Some 6-(2-Hyroxy phenyl)-4-(substituted phenyl) -3-oxo-2, 3, 4, 5- tetrahydro-1H-indazoles

Microwave Induced Synthesis and Anti bacterial Activity of Some 6-(2-Hyroxy phenyl)-4-(substituted phenyl) -3-oxo-2, 3, 4, 5- tetrahydro-1H-indazoles

The title compounds were synthesized by condensation of 2-hydroxy chalcones with ethylacetoacetate to get intermediate 3,5-diaryl-6-carbethoxy-2-cyclohexenone which were subsequently treated with hydrazine hydrate to afford the title compounds. All the transformation was carried out under microwave...

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Main Authors: N. S. Rao, B. Bajia, Y. K. Srivastava, Ravindra Kumar
Format: Article
Language:English
Published: Hindawi Limited 2008-01-01
Series:E-Journal of Chemistry
Online Access:http://dx.doi.org/10.1155/2008/739732
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spelling doaj-1e2bab4043ca468982e7f3b0e4c2dc872020-11-24T22:44:54ZengHindawi LimitedE-Journal of Chemistry0973-49452090-98102008-01-0151394210.1155/2008/739732Microwave Induced Synthesis and Anti bacterial Activity of Some 6-(2-Hyroxy phenyl)-4-(substituted phenyl) -3-oxo-2, 3, 4, 5- tetrahydro-1H-indazolesN. S. Rao0B. Bajia1Y. K. Srivastava2Ravindra Kumar3Department of Chemistry, M. P. Govt. P.G. College, Chittorgarh-312001, IndiaDepartment of Chemistry, M. P. Govt. P.G. College, Chittorgarh-312001, IndiaDepartment of Chemistry, M. P. Govt. P.G. College, Chittorgarh-312001, IndiaDepartment of Chemistry, M. P. Govt. P.G. College, Chittorgarh-312001, IndiaThe title compounds were synthesized by condensation of 2-hydroxy chalcones with ethylacetoacetate to get intermediate 3,5-diaryl-6-carbethoxy-2-cyclohexenone which were subsequently treated with hydrazine hydrate to afford the title compounds. All the transformation was carried out under microwave induced conditions. The synthesized compounds were screened for their antibacterial activity in vitro.http://dx.doi.org/10.1155/2008/739732
collection DOAJ
language English
format Article
sources DOAJ
author N. S. Rao
B. Bajia
Y. K. Srivastava
Ravindra Kumar
spellingShingle N. S. Rao
B. Bajia
Y. K. Srivastava
Ravindra Kumar
Microwave Induced Synthesis and Anti bacterial Activity of Some 6-(2-Hyroxy phenyl)-4-(substituted phenyl) -3-oxo-2, 3, 4, 5- tetrahydro-1H-indazoles
E-Journal of Chemistry
author_facet N. S. Rao
B. Bajia
Y. K. Srivastava
Ravindra Kumar
author_sort N. S. Rao
title Microwave Induced Synthesis and Anti bacterial Activity of Some 6-(2-Hyroxy phenyl)-4-(substituted phenyl) -3-oxo-2, 3, 4, 5- tetrahydro-1H-indazoles
title_short Microwave Induced Synthesis and Anti bacterial Activity of Some 6-(2-Hyroxy phenyl)-4-(substituted phenyl) -3-oxo-2, 3, 4, 5- tetrahydro-1H-indazoles
title_full Microwave Induced Synthesis and Anti bacterial Activity of Some 6-(2-Hyroxy phenyl)-4-(substituted phenyl) -3-oxo-2, 3, 4, 5- tetrahydro-1H-indazoles
title_fullStr Microwave Induced Synthesis and Anti bacterial Activity of Some 6-(2-Hyroxy phenyl)-4-(substituted phenyl) -3-oxo-2, 3, 4, 5- tetrahydro-1H-indazoles
title_full_unstemmed Microwave Induced Synthesis and Anti bacterial Activity of Some 6-(2-Hyroxy phenyl)-4-(substituted phenyl) -3-oxo-2, 3, 4, 5- tetrahydro-1H-indazoles
title_sort microwave induced synthesis and anti bacterial activity of some 6-(2-hyroxy phenyl)-4-(substituted phenyl) -3-oxo-2, 3, 4, 5- tetrahydro-1h-indazoles
publisher Hindawi Limited
series E-Journal of Chemistry
issn 0973-4945
2090-9810
publishDate 2008-01-01
description The title compounds were synthesized by condensation of 2-hydroxy chalcones with ethylacetoacetate to get intermediate 3,5-diaryl-6-carbethoxy-2-cyclohexenone which were subsequently treated with hydrazine hydrate to afford the title compounds. All the transformation was carried out under microwave induced conditions. The synthesized compounds were screened for their antibacterial activity in vitro.
url http://dx.doi.org/10.1155/2008/739732
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AT yksrivastava microwaveinducedsynthesisandantibacterialactivityofsome62hyroxyphenyl4substitutedphenyl3oxo2345tetrahydro1hindazoles
AT ravindrakumar microwaveinducedsynthesisandantibacterialactivityofsome62hyroxyphenyl4substitutedphenyl3oxo2345tetrahydro1hindazoles
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