Limited-sampling strategy models for estimating the pharmacokinetic parameters of 4-methylaminoantipyrine, an active metabolite of dipyrone

Limited-sampling strategy models for estimating the pharmacokinetic parameters of 4-methylaminoantipyrine, an active metabolite of dipyrone

Bioanalytical data from a bioequivalence study were used to develop limited-sampling strategy (LSS) models for estimating the area under the plasma concentration versus time curve (AUC) and the peak plasma concentration (Cmax) of 4-methylaminoantipyrine (MAA), an active metabolite of dipyrone. Twelv...

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Bibliographic Details
Main Authors: Suarez-Kurtz G., Ribeiro F.M., Estrela R.C.E., Vicente F.L., Struchiner C.J.
Format: Article
Language:English
Published: Associação Brasileira de Divulgação Científica 2001-01-01
Series:Brazilian Journal of Medical and Biological Research
Subjects:
dipyrone
4-methylaminoantipyrine
limited-sampling models
pharmacokinetics
bioequivalence
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2001001100017

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