BRONCHIAL ASTHMA IN INFANTS AND PRESCHOOL CHILDREN: SPECIFICS OF BASIC THERAPY

Due to the prevalence of allergic disease remains an urgent problem of atopy. Genetic factors play an important role in increasing the incidence, but we cannot forget about the Еnvironmental risk factors. The epigenetics explains the hereditary modifications of gene activity without changes in DNA s...

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Main Authors: E.A. Vishneva, R.M. Torshkhoeva, A.A. Alekseeva, Yu.G. Levina, K.E. Efendieva, A.Yu. Tomilova, N.I. Voznesenskaya
Format: Article
Language:English
Published: Paediatrician Publishers, LLC 2011-06-01
Series:Pediatričeskaâ Farmakologiâ
Online Access:https://pf.spr-journal.ru/jour/article/view/1274
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spelling doaj-1e16817e8c7b43b7a6edf48c1e536f302020-11-25T01:38:01ZengPaediatrician Publishers, LLCPediatričeskaâ Farmakologiâ1727-57762500-30892011-06-018370741269BRONCHIAL ASTHMA IN INFANTS AND PRESCHOOL CHILDREN: SPECIFICS OF BASIC THERAPYE.A. Vishneva0R.M. Torshkhoeva1A.A. Alekseeva2Yu.G. Levina3K.E. Efendieva4A.Yu. Tomilova5N.I. Voznesenskaya6Scientific Center of Children’s Health, Russian Academy of Medical Sciences, MoscowScientific Center of Children’s Health, Russian Academy of Medical Sciences, MoscowScientific Center of Children’s Health, Russian Academy of Medical Sciences, MoscowScientific Center of Children’s Health, Russian Academy of Medical Sciences, MoscowScientific Center of Children’s Health, Russian Academy of Medical Sciences, MoscowScientific Center of Children’s Health, Russian Academy of Medical Sciences, MoscowScientific Center of Children’s Health, Russian Academy of Medical Sciences, MoscowDue to the prevalence of allergic disease remains an urgent problem of atopy. Genetic factors play an important role in increasing the incidence, but we cannot forget about the Еnvironmental risk factors. The epigenetics explains the hereditary modifications of gene activity without changes in DNA sequence (for example, histone modifications, DNA methylation and chromatin’s architectonic changes). Study of biomechanics and airway remodeling in asthma causes remain one of the most actual at present. A special category of patients with asthma — young children — requires special attention due to the anatomical, phenotypic, and emotional specifics. Selection of the basic treatment for such patients should be aimed for maximizing the effective deposition of the drug.Key words: asthma, airway remodeling, preschool children, basic therapy.https://pf.spr-journal.ru/jour/article/view/1274
collection DOAJ
language English
format Article
sources DOAJ
author E.A. Vishneva
R.M. Torshkhoeva
A.A. Alekseeva
Yu.G. Levina
K.E. Efendieva
A.Yu. Tomilova
N.I. Voznesenskaya
spellingShingle E.A. Vishneva
R.M. Torshkhoeva
A.A. Alekseeva
Yu.G. Levina
K.E. Efendieva
A.Yu. Tomilova
N.I. Voznesenskaya
BRONCHIAL ASTHMA IN INFANTS AND PRESCHOOL CHILDREN: SPECIFICS OF BASIC THERAPY
Pediatričeskaâ Farmakologiâ
author_facet E.A. Vishneva
R.M. Torshkhoeva
A.A. Alekseeva
Yu.G. Levina
K.E. Efendieva
A.Yu. Tomilova
N.I. Voznesenskaya
author_sort E.A. Vishneva
title BRONCHIAL ASTHMA IN INFANTS AND PRESCHOOL CHILDREN: SPECIFICS OF BASIC THERAPY
title_short BRONCHIAL ASTHMA IN INFANTS AND PRESCHOOL CHILDREN: SPECIFICS OF BASIC THERAPY
title_full BRONCHIAL ASTHMA IN INFANTS AND PRESCHOOL CHILDREN: SPECIFICS OF BASIC THERAPY
title_fullStr BRONCHIAL ASTHMA IN INFANTS AND PRESCHOOL CHILDREN: SPECIFICS OF BASIC THERAPY
title_full_unstemmed BRONCHIAL ASTHMA IN INFANTS AND PRESCHOOL CHILDREN: SPECIFICS OF BASIC THERAPY
title_sort bronchial asthma in infants and preschool children: specifics of basic therapy
publisher Paediatrician Publishers, LLC
series Pediatričeskaâ Farmakologiâ
issn 1727-5776
2500-3089
publishDate 2011-06-01
description Due to the prevalence of allergic disease remains an urgent problem of atopy. Genetic factors play an important role in increasing the incidence, but we cannot forget about the Еnvironmental risk factors. The epigenetics explains the hereditary modifications of gene activity without changes in DNA sequence (for example, histone modifications, DNA methylation and chromatin’s architectonic changes). Study of biomechanics and airway remodeling in asthma causes remain one of the most actual at present. A special category of patients with asthma — young children — requires special attention due to the anatomical, phenotypic, and emotional specifics. Selection of the basic treatment for such patients should be aimed for maximizing the effective deposition of the drug.Key words: asthma, airway remodeling, preschool children, basic therapy.
url https://pf.spr-journal.ru/jour/article/view/1274
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