BRONCHIAL ASTHMA IN INFANTS AND PRESCHOOL CHILDREN: SPECIFICS OF BASIC THERAPY
Due to the prevalence of allergic disease remains an urgent problem of atopy. Genetic factors play an important role in increasing the incidence, but we cannot forget about the Еnvironmental risk factors. The epigenetics explains the hereditary modifications of gene activity without changes in DNA s...
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Paediatrician Publishers, LLC
2011-06-01
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Series: | Pediatričeskaâ Farmakologiâ |
Online Access: | https://pf.spr-journal.ru/jour/article/view/1274 |
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doaj-1e16817e8c7b43b7a6edf48c1e536f302020-11-25T01:38:01ZengPaediatrician Publishers, LLCPediatričeskaâ Farmakologiâ1727-57762500-30892011-06-018370741269BRONCHIAL ASTHMA IN INFANTS AND PRESCHOOL CHILDREN: SPECIFICS OF BASIC THERAPYE.A. Vishneva0R.M. Torshkhoeva1A.A. Alekseeva2Yu.G. Levina3K.E. Efendieva4A.Yu. Tomilova5N.I. Voznesenskaya6Scientific Center of Children’s Health, Russian Academy of Medical Sciences, MoscowScientific Center of Children’s Health, Russian Academy of Medical Sciences, MoscowScientific Center of Children’s Health, Russian Academy of Medical Sciences, MoscowScientific Center of Children’s Health, Russian Academy of Medical Sciences, MoscowScientific Center of Children’s Health, Russian Academy of Medical Sciences, MoscowScientific Center of Children’s Health, Russian Academy of Medical Sciences, MoscowScientific Center of Children’s Health, Russian Academy of Medical Sciences, MoscowDue to the prevalence of allergic disease remains an urgent problem of atopy. Genetic factors play an important role in increasing the incidence, but we cannot forget about the Еnvironmental risk factors. The epigenetics explains the hereditary modifications of gene activity without changes in DNA sequence (for example, histone modifications, DNA methylation and chromatin’s architectonic changes). Study of biomechanics and airway remodeling in asthma causes remain one of the most actual at present. A special category of patients with asthma — young children — requires special attention due to the anatomical, phenotypic, and emotional specifics. Selection of the basic treatment for such patients should be aimed for maximizing the effective deposition of the drug.Key words: asthma, airway remodeling, preschool children, basic therapy.https://pf.spr-journal.ru/jour/article/view/1274 |
collection |
DOAJ |
language |
English |
format |
Article |
sources |
DOAJ |
author |
E.A. Vishneva R.M. Torshkhoeva A.A. Alekseeva Yu.G. Levina K.E. Efendieva A.Yu. Tomilova N.I. Voznesenskaya |
spellingShingle |
E.A. Vishneva R.M. Torshkhoeva A.A. Alekseeva Yu.G. Levina K.E. Efendieva A.Yu. Tomilova N.I. Voznesenskaya BRONCHIAL ASTHMA IN INFANTS AND PRESCHOOL CHILDREN: SPECIFICS OF BASIC THERAPY Pediatričeskaâ Farmakologiâ |
author_facet |
E.A. Vishneva R.M. Torshkhoeva A.A. Alekseeva Yu.G. Levina K.E. Efendieva A.Yu. Tomilova N.I. Voznesenskaya |
author_sort |
E.A. Vishneva |
title |
BRONCHIAL ASTHMA IN INFANTS AND PRESCHOOL CHILDREN: SPECIFICS OF BASIC THERAPY |
title_short |
BRONCHIAL ASTHMA IN INFANTS AND PRESCHOOL CHILDREN: SPECIFICS OF BASIC THERAPY |
title_full |
BRONCHIAL ASTHMA IN INFANTS AND PRESCHOOL CHILDREN: SPECIFICS OF BASIC THERAPY |
title_fullStr |
BRONCHIAL ASTHMA IN INFANTS AND PRESCHOOL CHILDREN: SPECIFICS OF BASIC THERAPY |
title_full_unstemmed |
BRONCHIAL ASTHMA IN INFANTS AND PRESCHOOL CHILDREN: SPECIFICS OF BASIC THERAPY |
title_sort |
bronchial asthma in infants and preschool children: specifics of basic therapy |
publisher |
Paediatrician Publishers, LLC |
series |
Pediatričeskaâ Farmakologiâ |
issn |
1727-5776 2500-3089 |
publishDate |
2011-06-01 |
description |
Due to the prevalence of allergic disease remains an urgent problem of atopy. Genetic factors play an important role in increasing the incidence, but we cannot forget about the Еnvironmental risk factors. The epigenetics explains the hereditary modifications of gene activity without changes in DNA sequence (for example, histone modifications, DNA methylation and chromatin’s architectonic changes). Study of biomechanics and airway remodeling in asthma causes remain one of the most actual at present. A special category of patients with asthma — young children — requires special attention due to the anatomical, phenotypic, and emotional specifics. Selection of the basic treatment for such patients should be aimed for maximizing the effective deposition of the drug.Key words: asthma, airway remodeling, preschool children, basic therapy. |
url |
https://pf.spr-journal.ru/jour/article/view/1274 |
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