Comparison of the Efficacy of Two Novel Antitubercular Agents in Free and Liposome-Encapsulated Formulations

Comparison of the Efficacy of Two Novel Antitubercular Agents in Free and Liposome-Encapsulated Formulations

Tuberculosis is one of the top ten causes of death worldwide, and due to the appearance of drug-resistant strains, the development of new antituberculotic agents is a pressing challenge. Employing an in silico docking method, two coumaran (2,3-dihydrobenzofuran) derivatives—TB501 and TB515—were dete...

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Bibliographic Details
Main Authors: Nikoletta Kósa, Ádám Zolcsák, István Voszka, Gabriella Csík, Kata Horváti, Lilla Horváth, Szilvia Bősze, Levente Herenyi
Format: Article
Language:English
Published: MDPI AG 2021-02-01
Series:International Journal of Molecular Sciences
Subjects:
coumaran
2,3-dihydrobenzofuran
pH-sensitive stealth liposome
monocomponent liposome
dynamic light scattering
absorption spectrometry
Online Access:https://www.mdpi.com/1422-0067/22/5/2457

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https://www.mdpi.com/1422-0067/22/5/2457

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