Multifaceted Applications of Chitosan in Cancer Drug Delivery and Therapy

Chitosan is a versatile polysaccharide of biological origin. Due to the biocompatible and biodegradable nature of chitosan, it is intensively utilized in biomedical applications in scaffold engineering as an absorption enhancer, and for bioactive and controlled drug release. In cancer therapy, chito...

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Main Authors: Anish Babu, Rajagopal Ramesh
Format: Article
Language:English
Published: MDPI AG 2017-03-01
Series:Marine Drugs
Subjects:
Online Access:http://www.mdpi.com/1660-3397/15/4/96
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spelling doaj-1e0c7f9903694ab099ff703817bdb3692020-11-24T21:56:02ZengMDPI AGMarine Drugs1660-33972017-03-011549610.3390/md15040096md15040096Multifaceted Applications of Chitosan in Cancer Drug Delivery and TherapyAnish Babu0Rajagopal Ramesh1Department of Pathology, University of Oklahoma Health Sciences Center, Oklahoma City, OK 73104, USADepartment of Pathology, University of Oklahoma Health Sciences Center, Oklahoma City, OK 73104, USAChitosan is a versatile polysaccharide of biological origin. Due to the biocompatible and biodegradable nature of chitosan, it is intensively utilized in biomedical applications in scaffold engineering as an absorption enhancer, and for bioactive and controlled drug release. In cancer therapy, chitosan has multifaceted applications, such as assisting in gene delivery and chemotherapeutic delivery, and as an immunoadjuvant for vaccines. The present review highlights the recent applications of chitosan and chitosan derivatives in cancer therapy.http://www.mdpi.com/1660-3397/15/4/96chitosangene deliverydrug deliveryadjuvantcancernanoparticle
collection DOAJ
language English
format Article
sources DOAJ
author Anish Babu
Rajagopal Ramesh
spellingShingle Anish Babu
Rajagopal Ramesh
Multifaceted Applications of Chitosan in Cancer Drug Delivery and Therapy
Marine Drugs
chitosan
gene delivery
drug delivery
adjuvant
cancer
nanoparticle
author_facet Anish Babu
Rajagopal Ramesh
author_sort Anish Babu
title Multifaceted Applications of Chitosan in Cancer Drug Delivery and Therapy
title_short Multifaceted Applications of Chitosan in Cancer Drug Delivery and Therapy
title_full Multifaceted Applications of Chitosan in Cancer Drug Delivery and Therapy
title_fullStr Multifaceted Applications of Chitosan in Cancer Drug Delivery and Therapy
title_full_unstemmed Multifaceted Applications of Chitosan in Cancer Drug Delivery and Therapy
title_sort multifaceted applications of chitosan in cancer drug delivery and therapy
publisher MDPI AG
series Marine Drugs
issn 1660-3397
publishDate 2017-03-01
description Chitosan is a versatile polysaccharide of biological origin. Due to the biocompatible and biodegradable nature of chitosan, it is intensively utilized in biomedical applications in scaffold engineering as an absorption enhancer, and for bioactive and controlled drug release. In cancer therapy, chitosan has multifaceted applications, such as assisting in gene delivery and chemotherapeutic delivery, and as an immunoadjuvant for vaccines. The present review highlights the recent applications of chitosan and chitosan derivatives in cancer therapy.
topic chitosan
gene delivery
drug delivery
adjuvant
cancer
nanoparticle
url http://www.mdpi.com/1660-3397/15/4/96
work_keys_str_mv AT anishbabu multifacetedapplicationsofchitosanincancerdrugdeliveryandtherapy
AT rajagopalramesh multifacetedapplicationsofchitosanincancerdrugdeliveryandtherapy
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