Single-cell and bulk transcriptomics of the liver reveals potential targets of NASH with fibrosis

Single-cell and bulk transcriptomics of the liver reveals potential targets of NASH with fibrosis

Abstract Fibrosis is characterized by the excessive production of collagen and other extracellular matrix (ECM) components and represents a leading cause of morbidity and mortality worldwide. Previous studies of nonalcoholic steatohepatitis (NASH) with fibrosis were largely restricted to bulk transc...

Full description

Bibliographic Details
Main Authors: Zhong-Yi Wang, Adrian Keogh, Annick Waldt, Rachel Cuttat, Marilisa Neri, Shanshan Zhu, Sven Schuierer, Alexandra Ruchti, Christophe Crochemore, Judith Knehr, Julie Bastien, Iwona Ksiazek, Daniel Sánchez-Taltavull, Hui Ge, Jing Wu, Guglielmo Roma, Stephen B. Helliwell, Deborah Stroka, Florian Nigsch
Format: Article
Language:English
Published: Nature Publishing Group 2021-09-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-021-98806-y

Internet

https://doi.org/10.1038/s41598-021-98806-y

Similar Items