Environmental Enrichment and Physical Exercise Attenuate the Depressive-Like Effects Induced by Social Isolation Stress in Rats

Environmental Enrichment and Physical Exercise Attenuate the Depressive-Like Effects Induced by Social Isolation Stress in Rats

We assessed the antidepressant-like effects of environmental enrichment (EE) and physical exercise (PE) compared with the selective serotonin reuptake inhibitor fluoxetine against the depression-related neurobehavioral alterations induced by postweaning social isolation (SI) in rats. After 1 month o...

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Bibliographic Details
Main Authors: Juan C. Brenes, Jaime Fornaguera, Andrey Sequeira-Cordero
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-05-01
Series:Frontiers in Pharmacology
Subjects:
social isolation
environmental enrichment
physical exercise
antidepressant effect
serotonin
hippocampus
Online Access:https://www.frontiersin.org/article/10.3389/fphar.2020.00804/full

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