Analysis of risk factors for perioperative hidden blood loss in unilateral biportal endoscopic spine surgery: a retrospective multicenter study
Abstract Background Hidden blood loss (HBL) represents an important complication of unilateral biportal endoscopic (UBE) spine surgery. This study aimed to evaluate HBL and its possible risk factors among patients undergoing UBE surgery for lumbar degenerative diseases. Methods This multicentric ret...
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doaj-1df50fef080c46499ae1de521889fa942021-09-19T11:41:50ZengBMCJournal of Orthopaedic Surgery and Research1749-799X2021-09-011611910.1186/s13018-021-02698-7Analysis of risk factors for perioperative hidden blood loss in unilateral biportal endoscopic spine surgery: a retrospective multicenter studyHaosheng Wang0Kai Wang1Bin Lv2Wenle Li3Tingting Fan4Jianwu Zhao5Mingyang Kang6Rongpeng Dong7Yang Qu8Department of Orthopedics, Second Hospital of Jilin UniversityDepartment of Orthopedics, West China Hospital, Sichuan UniversityDepartment of Orthopedics, Union Hospital, Tongji Medical College, Huazhong University of Science and TechnologyDepartment of Orthopedics, Liuzhou People’s HospitalDepartment of Endocrinology, Second Hospital of Jilin UniversityDepartment of Orthopedics, Second Hospital of Jilin UniversityDepartment of Orthopedics, Second Hospital of Jilin UniversityDepartment of Orthopedics, Second Hospital of Jilin UniversityDepartment of Orthopedics, Second Hospital of Jilin UniversityAbstract Background Hidden blood loss (HBL) represents an important complication of unilateral biportal endoscopic (UBE) spine surgery. This study aimed to evaluate HBL and its possible risk factors among patients undergoing UBE surgery for lumbar degenerative diseases. Methods This multicentric retrospective study was conducted in 3 different medical centers between July 2020 and April 2021. Data of patients who underwent UBE surgery were extracted by electronic medical record system. The patient’s demographic characteristics and blood loss-related parameters were recorded. We calculated the amount of HBL and explored the association between patient’s characteristics and HBL using Pearson or Spearman correlation analysis. Multivariate linear regression analysis was conducted to identify independent risk factors of HBL. Results A total of 136 patients (55 females and 81 males, age range 43 to 74 years) were included in this study. A substantial amount of HBL (469.5 ± 195.3 ml, 57.6% of TBL, total blood loss) occurred following UBE surgery. Multiple linear regression analysis indicated that the risk factors of HBL were as follows: age (P = 0.000), number of fusion levels (P = 0.015), American Society of Anesthesiologists (ASA) classification (P = 0.046), surgery time (P = 0.017), patient’s blood volume (PBV, P = 0.026), total blood loss (TBL, P = 0.001), postoperative (i.e., day 2 or 3) hematocrit (Hct, P = 0.034), Hct loss (P = 0.005), and fibrinogen (P = 0.028). Conclusions A certain amount of HBL occurs in UBE surgery and cannot be ignored in daily clinical practice. The age, number of fusion levels, ASA classification, surgery time, PBV, TBL, postoperative Hct, Hct loss, and fibrinogen are independent risk factors for HBL.https://doi.org/10.1186/s13018-021-02698-7Hidden blood loss (HBL)Risk factorsPerioperativeMultiple linear regressionUnilateral biportal endoscopic (UBE) |
collection |
DOAJ |
language |
English |
format |
Article |
sources |
DOAJ |
author |
Haosheng Wang Kai Wang Bin Lv Wenle Li Tingting Fan Jianwu Zhao Mingyang Kang Rongpeng Dong Yang Qu |
spellingShingle |
Haosheng Wang Kai Wang Bin Lv Wenle Li Tingting Fan Jianwu Zhao Mingyang Kang Rongpeng Dong Yang Qu Analysis of risk factors for perioperative hidden blood loss in unilateral biportal endoscopic spine surgery: a retrospective multicenter study Journal of Orthopaedic Surgery and Research Hidden blood loss (HBL) Risk factors Perioperative Multiple linear regression Unilateral biportal endoscopic (UBE) |
author_facet |
Haosheng Wang Kai Wang Bin Lv Wenle Li Tingting Fan Jianwu Zhao Mingyang Kang Rongpeng Dong Yang Qu |
author_sort |
Haosheng Wang |
title |
Analysis of risk factors for perioperative hidden blood loss in unilateral biportal endoscopic spine surgery: a retrospective multicenter study |
title_short |
Analysis of risk factors for perioperative hidden blood loss in unilateral biportal endoscopic spine surgery: a retrospective multicenter study |
title_full |
Analysis of risk factors for perioperative hidden blood loss in unilateral biportal endoscopic spine surgery: a retrospective multicenter study |
title_fullStr |
Analysis of risk factors for perioperative hidden blood loss in unilateral biportal endoscopic spine surgery: a retrospective multicenter study |
title_full_unstemmed |
Analysis of risk factors for perioperative hidden blood loss in unilateral biportal endoscopic spine surgery: a retrospective multicenter study |
title_sort |
analysis of risk factors for perioperative hidden blood loss in unilateral biportal endoscopic spine surgery: a retrospective multicenter study |
publisher |
BMC |
series |
Journal of Orthopaedic Surgery and Research |
issn |
1749-799X |
publishDate |
2021-09-01 |
description |
Abstract Background Hidden blood loss (HBL) represents an important complication of unilateral biportal endoscopic (UBE) spine surgery. This study aimed to evaluate HBL and its possible risk factors among patients undergoing UBE surgery for lumbar degenerative diseases. Methods This multicentric retrospective study was conducted in 3 different medical centers between July 2020 and April 2021. Data of patients who underwent UBE surgery were extracted by electronic medical record system. The patient’s demographic characteristics and blood loss-related parameters were recorded. We calculated the amount of HBL and explored the association between patient’s characteristics and HBL using Pearson or Spearman correlation analysis. Multivariate linear regression analysis was conducted to identify independent risk factors of HBL. Results A total of 136 patients (55 females and 81 males, age range 43 to 74 years) were included in this study. A substantial amount of HBL (469.5 ± 195.3 ml, 57.6% of TBL, total blood loss) occurred following UBE surgery. Multiple linear regression analysis indicated that the risk factors of HBL were as follows: age (P = 0.000), number of fusion levels (P = 0.015), American Society of Anesthesiologists (ASA) classification (P = 0.046), surgery time (P = 0.017), patient’s blood volume (PBV, P = 0.026), total blood loss (TBL, P = 0.001), postoperative (i.e., day 2 or 3) hematocrit (Hct, P = 0.034), Hct loss (P = 0.005), and fibrinogen (P = 0.028). Conclusions A certain amount of HBL occurs in UBE surgery and cannot be ignored in daily clinical practice. The age, number of fusion levels, ASA classification, surgery time, PBV, TBL, postoperative Hct, Hct loss, and fibrinogen are independent risk factors for HBL. |
topic |
Hidden blood loss (HBL) Risk factors Perioperative Multiple linear regression Unilateral biportal endoscopic (UBE) |
url |
https://doi.org/10.1186/s13018-021-02698-7 |
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