Analysis of risk factors for perioperative hidden blood loss in unilateral biportal endoscopic spine surgery: a retrospective multicenter study

Abstract Background Hidden blood loss (HBL) represents an important complication of unilateral biportal endoscopic (UBE) spine surgery. This study aimed to evaluate HBL and its possible risk factors among patients undergoing UBE surgery for lumbar degenerative diseases. Methods This multicentric ret...

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Main Authors: Haosheng Wang, Kai Wang, Bin Lv, Wenle Li, Tingting Fan, Jianwu Zhao, Mingyang Kang, Rongpeng Dong, Yang Qu
Format: Article
Language:English
Published: BMC 2021-09-01
Series:Journal of Orthopaedic Surgery and Research
Subjects:
Online Access:https://doi.org/10.1186/s13018-021-02698-7
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spelling doaj-1df50fef080c46499ae1de521889fa942021-09-19T11:41:50ZengBMCJournal of Orthopaedic Surgery and Research1749-799X2021-09-011611910.1186/s13018-021-02698-7Analysis of risk factors for perioperative hidden blood loss in unilateral biportal endoscopic spine surgery: a retrospective multicenter studyHaosheng Wang0Kai Wang1Bin Lv2Wenle Li3Tingting Fan4Jianwu Zhao5Mingyang Kang6Rongpeng Dong7Yang Qu8Department of Orthopedics, Second Hospital of Jilin UniversityDepartment of Orthopedics, West China Hospital, Sichuan UniversityDepartment of Orthopedics, Union Hospital, Tongji Medical College, Huazhong University of Science and TechnologyDepartment of Orthopedics, Liuzhou People’s HospitalDepartment of Endocrinology, Second Hospital of Jilin UniversityDepartment of Orthopedics, Second Hospital of Jilin UniversityDepartment of Orthopedics, Second Hospital of Jilin UniversityDepartment of Orthopedics, Second Hospital of Jilin UniversityDepartment of Orthopedics, Second Hospital of Jilin UniversityAbstract Background Hidden blood loss (HBL) represents an important complication of unilateral biportal endoscopic (UBE) spine surgery. This study aimed to evaluate HBL and its possible risk factors among patients undergoing UBE surgery for lumbar degenerative diseases. Methods This multicentric retrospective study was conducted in 3 different medical centers between July 2020 and April 2021. Data of patients who underwent UBE surgery were extracted by electronic medical record system. The patient’s demographic characteristics and blood loss-related parameters were recorded. We calculated the amount of HBL and explored the association between patient’s characteristics and HBL using Pearson or Spearman correlation analysis. Multivariate linear regression analysis was conducted to identify independent risk factors of HBL. Results A total of 136 patients (55 females and 81 males, age range 43 to 74 years) were included in this study. A substantial amount of HBL (469.5 ± 195.3 ml, 57.6% of TBL, total blood loss) occurred following UBE surgery. Multiple linear regression analysis indicated that the risk factors of HBL were as follows: age (P = 0.000), number of fusion levels (P = 0.015), American Society of Anesthesiologists (ASA) classification (P = 0.046), surgery time (P = 0.017), patient’s blood volume (PBV, P = 0.026), total blood loss (TBL, P = 0.001), postoperative (i.e., day 2 or 3) hematocrit (Hct, P = 0.034), Hct loss (P = 0.005), and fibrinogen (P = 0.028). Conclusions A certain amount of HBL occurs in UBE surgery and cannot be ignored in daily clinical practice. The age, number of fusion levels, ASA classification, surgery time, PBV, TBL, postoperative Hct, Hct loss, and fibrinogen are independent risk factors for HBL.https://doi.org/10.1186/s13018-021-02698-7Hidden blood loss (HBL)Risk factorsPerioperativeMultiple linear regressionUnilateral biportal endoscopic (UBE)
collection DOAJ
language English
format Article
sources DOAJ
author Haosheng Wang
Kai Wang
Bin Lv
Wenle Li
Tingting Fan
Jianwu Zhao
Mingyang Kang
Rongpeng Dong
Yang Qu
spellingShingle Haosheng Wang
Kai Wang
Bin Lv
Wenle Li
Tingting Fan
Jianwu Zhao
Mingyang Kang
Rongpeng Dong
Yang Qu
Analysis of risk factors for perioperative hidden blood loss in unilateral biportal endoscopic spine surgery: a retrospective multicenter study
Journal of Orthopaedic Surgery and Research
Hidden blood loss (HBL)
Risk factors
Perioperative
Multiple linear regression
Unilateral biportal endoscopic (UBE)
author_facet Haosheng Wang
Kai Wang
Bin Lv
Wenle Li
Tingting Fan
Jianwu Zhao
Mingyang Kang
Rongpeng Dong
Yang Qu
author_sort Haosheng Wang
title Analysis of risk factors for perioperative hidden blood loss in unilateral biportal endoscopic spine surgery: a retrospective multicenter study
title_short Analysis of risk factors for perioperative hidden blood loss in unilateral biportal endoscopic spine surgery: a retrospective multicenter study
title_full Analysis of risk factors for perioperative hidden blood loss in unilateral biportal endoscopic spine surgery: a retrospective multicenter study
title_fullStr Analysis of risk factors for perioperative hidden blood loss in unilateral biportal endoscopic spine surgery: a retrospective multicenter study
title_full_unstemmed Analysis of risk factors for perioperative hidden blood loss in unilateral biportal endoscopic spine surgery: a retrospective multicenter study
title_sort analysis of risk factors for perioperative hidden blood loss in unilateral biportal endoscopic spine surgery: a retrospective multicenter study
publisher BMC
series Journal of Orthopaedic Surgery and Research
issn 1749-799X
publishDate 2021-09-01
description Abstract Background Hidden blood loss (HBL) represents an important complication of unilateral biportal endoscopic (UBE) spine surgery. This study aimed to evaluate HBL and its possible risk factors among patients undergoing UBE surgery for lumbar degenerative diseases. Methods This multicentric retrospective study was conducted in 3 different medical centers between July 2020 and April 2021. Data of patients who underwent UBE surgery were extracted by electronic medical record system. The patient’s demographic characteristics and blood loss-related parameters were recorded. We calculated the amount of HBL and explored the association between patient’s characteristics and HBL using Pearson or Spearman correlation analysis. Multivariate linear regression analysis was conducted to identify independent risk factors of HBL. Results A total of 136 patients (55 females and 81 males, age range 43 to 74 years) were included in this study. A substantial amount of HBL (469.5 ± 195.3 ml, 57.6% of TBL, total blood loss) occurred following UBE surgery. Multiple linear regression analysis indicated that the risk factors of HBL were as follows: age (P = 0.000), number of fusion levels (P = 0.015), American Society of Anesthesiologists (ASA) classification (P = 0.046), surgery time (P = 0.017), patient’s blood volume (PBV, P = 0.026), total blood loss (TBL, P = 0.001), postoperative (i.e., day 2 or 3) hematocrit (Hct, P = 0.034), Hct loss (P = 0.005), and fibrinogen (P = 0.028). Conclusions A certain amount of HBL occurs in UBE surgery and cannot be ignored in daily clinical practice. The age, number of fusion levels, ASA classification, surgery time, PBV, TBL, postoperative Hct, Hct loss, and fibrinogen are independent risk factors for HBL.
topic Hidden blood loss (HBL)
Risk factors
Perioperative
Multiple linear regression
Unilateral biportal endoscopic (UBE)
url https://doi.org/10.1186/s13018-021-02698-7
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