Sclerosing angiomatoid nodular transformation of the spleen masquerading as a sarcoma metastasis
We report a case of sclerosing angiomatoid nodular transformation (SANT) of the spleen presenting as an incidental splenic mass in a patient with a history of retroperitoneal spindle cell sarcoma. Imaging studies and preoperative fine needle biopsy failed to differentiate this lesion from other vasc...
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doaj-1df3d9d0bb27414a8495495d13ed29b72020-11-25T03:27:54ZengSAGE PublishingRare Tumors2036-36032036-36132010-12-0124e45e4510.4081/rt.2010.e45Sclerosing angiomatoid nodular transformation of the spleen masquerading as a sarcoma metastasisLalitha SitaramanKristina A. MatkowskyjJeffrey D. WayneJohn G. LinnWe report a case of sclerosing angiomatoid nodular transformation (SANT) of the spleen presenting as an incidental splenic mass in a patient with a history of retroperitoneal spindle cell sarcoma. Imaging studies and preoperative fine needle biopsy failed to differentiate this lesion from other vascular splenic lesions or a metastatic focus of a prior sarcoma. The patient was treated with splenectomy, which has proved both diagnostic and therapeutic in this and other cases of SANT. Although histology can lead to the diagnosis of vascular tumor, immunohistochemistry is the only way to confirm the diagnosis of SANT. The etiology of SANT is unknown. SANT of the spleen is a benign lesion that does not recur after splenectomy.http://www.pagepress.org/journals/index.php/rt/article/view/1821SurgeryOncologySarcomaSpleen: SANT |
collection |
DOAJ |
language |
English |
format |
Article |
sources |
DOAJ |
author |
Lalitha Sitaraman Kristina A. Matkowskyj Jeffrey D. Wayne John G. Linn |
spellingShingle |
Lalitha Sitaraman Kristina A. Matkowskyj Jeffrey D. Wayne John G. Linn Sclerosing angiomatoid nodular transformation of the spleen masquerading as a sarcoma metastasis Rare Tumors Surgery Oncology Sarcoma Spleen: SANT |
author_facet |
Lalitha Sitaraman Kristina A. Matkowskyj Jeffrey D. Wayne John G. Linn |
author_sort |
Lalitha Sitaraman |
title |
Sclerosing angiomatoid nodular transformation of the spleen masquerading as a sarcoma metastasis |
title_short |
Sclerosing angiomatoid nodular transformation of the spleen masquerading as a sarcoma metastasis |
title_full |
Sclerosing angiomatoid nodular transformation of the spleen masquerading as a sarcoma metastasis |
title_fullStr |
Sclerosing angiomatoid nodular transformation of the spleen masquerading as a sarcoma metastasis |
title_full_unstemmed |
Sclerosing angiomatoid nodular transformation of the spleen masquerading as a sarcoma metastasis |
title_sort |
sclerosing angiomatoid nodular transformation of the spleen masquerading as a sarcoma metastasis |
publisher |
SAGE Publishing |
series |
Rare Tumors |
issn |
2036-3603 2036-3613 |
publishDate |
2010-12-01 |
description |
We report a case of sclerosing angiomatoid nodular transformation (SANT) of the spleen presenting as an incidental splenic mass in a patient with a history of retroperitoneal spindle cell sarcoma. Imaging studies and preoperative fine needle biopsy failed to differentiate this lesion from other vascular splenic lesions or a metastatic focus of a prior sarcoma. The patient was treated with splenectomy, which has proved both diagnostic and therapeutic in this and other cases of SANT. Although histology can lead to the diagnosis of vascular tumor, immunohistochemistry is the only way to confirm the diagnosis of SANT. The etiology of SANT is unknown. SANT of the spleen is a benign lesion that does not recur after splenectomy. |
topic |
Surgery Oncology Sarcoma Spleen: SANT |
url |
http://www.pagepress.org/journals/index.php/rt/article/view/1821 |
work_keys_str_mv |
AT lalithasitaraman sclerosingangiomatoidnodulartransformationofthespleenmasqueradingasasarcomametastasis AT kristinaamatkowskyj sclerosingangiomatoidnodulartransformationofthespleenmasqueradingasasarcomametastasis AT jeffreydwayne sclerosingangiomatoidnodulartransformationofthespleenmasqueradingasasarcomametastasis AT johnglinn sclerosingangiomatoidnodulartransformationofthespleenmasqueradingasasarcomametastasis |
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1724586515644809216 |