Sclerosing angiomatoid nodular transformation of the spleen masquerading as a sarcoma metastasis

We report a case of sclerosing angiomatoid nodular transformation (SANT) of the spleen presenting as an incidental splenic mass in a patient with a history of retroperitoneal spindle cell sarcoma. Imaging studies and preoperative fine needle biopsy failed to differentiate this lesion from other vasc...

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Main Authors: Lalitha Sitaraman, Kristina A. Matkowskyj, Jeffrey D. Wayne, John G. Linn
Format: Article
Language:English
Published: SAGE Publishing 2010-12-01
Series:Rare Tumors
Subjects:
Online Access:http://www.pagepress.org/journals/index.php/rt/article/view/1821
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spelling doaj-1df3d9d0bb27414a8495495d13ed29b72020-11-25T03:27:54ZengSAGE PublishingRare Tumors2036-36032036-36132010-12-0124e45e4510.4081/rt.2010.e45Sclerosing angiomatoid nodular transformation of the spleen masquerading as a sarcoma metastasisLalitha SitaramanKristina A. MatkowskyjJeffrey D. WayneJohn G. LinnWe report a case of sclerosing angiomatoid nodular transformation (SANT) of the spleen presenting as an incidental splenic mass in a patient with a history of retroperitoneal spindle cell sarcoma. Imaging studies and preoperative fine needle biopsy failed to differentiate this lesion from other vascular splenic lesions or a metastatic focus of a prior sarcoma. The patient was treated with splenectomy, which has proved both diagnostic and therapeutic in this and other cases of SANT. Although histology can lead to the diagnosis of vascular tumor, immuno­histochemistry is the only way to confirm the diagnosis of SANT. The etiology of SANT is unknown. SANT of the spleen is a benign lesion that does not recur after splenectomy.http://www.pagepress.org/journals/index.php/rt/article/view/1821SurgeryOncologySarcomaSpleen: SANT
collection DOAJ
language English
format Article
sources DOAJ
author Lalitha Sitaraman
Kristina A. Matkowskyj
Jeffrey D. Wayne
John G. Linn
spellingShingle Lalitha Sitaraman
Kristina A. Matkowskyj
Jeffrey D. Wayne
John G. Linn
Sclerosing angiomatoid nodular transformation of the spleen masquerading as a sarcoma metastasis
Rare Tumors
Surgery
Oncology
Sarcoma
Spleen: SANT
author_facet Lalitha Sitaraman
Kristina A. Matkowskyj
Jeffrey D. Wayne
John G. Linn
author_sort Lalitha Sitaraman
title Sclerosing angiomatoid nodular transformation of the spleen masquerading as a sarcoma metastasis
title_short Sclerosing angiomatoid nodular transformation of the spleen masquerading as a sarcoma metastasis
title_full Sclerosing angiomatoid nodular transformation of the spleen masquerading as a sarcoma metastasis
title_fullStr Sclerosing angiomatoid nodular transformation of the spleen masquerading as a sarcoma metastasis
title_full_unstemmed Sclerosing angiomatoid nodular transformation of the spleen masquerading as a sarcoma metastasis
title_sort sclerosing angiomatoid nodular transformation of the spleen masquerading as a sarcoma metastasis
publisher SAGE Publishing
series Rare Tumors
issn 2036-3603
2036-3613
publishDate 2010-12-01
description We report a case of sclerosing angiomatoid nodular transformation (SANT) of the spleen presenting as an incidental splenic mass in a patient with a history of retroperitoneal spindle cell sarcoma. Imaging studies and preoperative fine needle biopsy failed to differentiate this lesion from other vascular splenic lesions or a metastatic focus of a prior sarcoma. The patient was treated with splenectomy, which has proved both diagnostic and therapeutic in this and other cases of SANT. Although histology can lead to the diagnosis of vascular tumor, immuno­histochemistry is the only way to confirm the diagnosis of SANT. The etiology of SANT is unknown. SANT of the spleen is a benign lesion that does not recur after splenectomy.
topic Surgery
Oncology
Sarcoma
Spleen: SANT
url http://www.pagepress.org/journals/index.php/rt/article/view/1821
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AT jeffreydwayne sclerosingangiomatoidnodulartransformationofthespleenmasqueradingasasarcomametastasis
AT johnglinn sclerosingangiomatoidnodulartransformationofthespleenmasqueradingasasarcomametastasis
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