Early hydroxychloroquine and azithromycin as combined therapy for COVID-19: a case series

Coronavirus disease 2019 (COVID-19) is a worldwide outbreak caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). The World Health Organization (WHO) has declared it as a public health emergency of international concern (PHEIC) and eventually a pandemic. Many clinical trials have b...

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Main Authors: Siswanto Siswanto, Oktaviarum S. Utama, Agit S. Adisetiadi, Maria E. Pranasakti, Mohamad Saifudin Hakim
Format: Article
Language:English
Published: Universitas Gadjah Mada 2020-06-01
Series:Journal of the Medical Sciences
Subjects:
Online Access:https://jurnal.ugm.ac.id/bik/article/view/56441
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spelling doaj-1debdfb1393e4dc8af7cfccf6c8f6c362020-11-25T03:55:09ZengUniversitas Gadjah MadaJournal of the Medical Sciences0126-13122356-39312020-06-0152310.19106/JMedSciSI00520320201627002Early hydroxychloroquine and azithromycin as combined therapy for COVID-19: a case seriesSiswanto Siswanto0Oktaviarum S. Utama1Agit S. Adisetiadi2Maria E. Pranasakti3Mohamad Saifudin Hakim4Department of Pulmonology and Respiratory Medicine, Academic Hospital, Department of Physiology, Faculty of Medicine, Public Health and Nursing, Universitas Gadjah Mada, YogyakartaDepartment of Pulmonology and Respiratory Medicine, Academic Hospital, Faculty of Medicine, Public Health and Nursing, Universitas Gadjah Mada, YogyakartaDepartment of Internal Medicine, Academic Hospital, Faculty of Medicine, Public Health and Nursing, Universitas Gadjah Mada, YogyakartaDepartment of Internal Medicine, Academic Hospital, Faculty of Medicine, Public Health and Nursing, Universitas Gadjah Mada, YogyakartaDepartment of Microbiology, Faculty of Medicine, Public Health and Nursing, Universitas Gadjah Mada, YogyakartaCoronavirus disease 2019 (COVID-19) is a worldwide outbreak caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). The World Health Organization (WHO) has declared it as a public health emergency of international concern (PHEIC) and eventually a pandemic. Many clinical trials have been conducted to investigate potential and effective therapies for COVID-19. Here we reported the outcome of three COVID-19 cases treated early with the combination of hydroxychloroquine and azithromycin. Early treatments of suspected or confirmed positive COVID-19 cases with this combination therapy is to avoid disease progressions into a more severe and irreversible state. In these cases, clinical, radiological, and laboratory features were followed up. No complications were observed. The COVID-19 patients treated with this early combination therapy showed good clinical and virological responses.https://jurnal.ugm.ac.id/bik/article/view/56441azithromycincovid-19hydroxychloroquinesars-cov-2therapy
collection DOAJ
language English
format Article
sources DOAJ
author Siswanto Siswanto
Oktaviarum S. Utama
Agit S. Adisetiadi
Maria E. Pranasakti
Mohamad Saifudin Hakim
spellingShingle Siswanto Siswanto
Oktaviarum S. Utama
Agit S. Adisetiadi
Maria E. Pranasakti
Mohamad Saifudin Hakim
Early hydroxychloroquine and azithromycin as combined therapy for COVID-19: a case series
Journal of the Medical Sciences
azithromycin
covid-19
hydroxychloroquine
sars-cov-2
therapy
author_facet Siswanto Siswanto
Oktaviarum S. Utama
Agit S. Adisetiadi
Maria E. Pranasakti
Mohamad Saifudin Hakim
author_sort Siswanto Siswanto
title Early hydroxychloroquine and azithromycin as combined therapy for COVID-19: a case series
title_short Early hydroxychloroquine and azithromycin as combined therapy for COVID-19: a case series
title_full Early hydroxychloroquine and azithromycin as combined therapy for COVID-19: a case series
title_fullStr Early hydroxychloroquine and azithromycin as combined therapy for COVID-19: a case series
title_full_unstemmed Early hydroxychloroquine and azithromycin as combined therapy for COVID-19: a case series
title_sort early hydroxychloroquine and azithromycin as combined therapy for covid-19: a case series
publisher Universitas Gadjah Mada
series Journal of the Medical Sciences
issn 0126-1312
2356-3931
publishDate 2020-06-01
description Coronavirus disease 2019 (COVID-19) is a worldwide outbreak caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). The World Health Organization (WHO) has declared it as a public health emergency of international concern (PHEIC) and eventually a pandemic. Many clinical trials have been conducted to investigate potential and effective therapies for COVID-19. Here we reported the outcome of three COVID-19 cases treated early with the combination of hydroxychloroquine and azithromycin. Early treatments of suspected or confirmed positive COVID-19 cases with this combination therapy is to avoid disease progressions into a more severe and irreversible state. In these cases, clinical, radiological, and laboratory features were followed up. No complications were observed. The COVID-19 patients treated with this early combination therapy showed good clinical and virological responses.
topic azithromycin
covid-19
hydroxychloroquine
sars-cov-2
therapy
url https://jurnal.ugm.ac.id/bik/article/view/56441
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