Galectins in Intra- and Extracellular Vesicles

Carbohydrate-binding galectins are expressed in various tissues of multicellular organisms. They are involved in autophagy, cell migration, immune response, inflammation, intracellular transport, and signaling. In recent years, novel roles of galectin-interaction with membrane components have been c...

Full description

Bibliographic Details
Main Authors:	Sebastian Bänfer, Ralf Jacob
Format:	Article
Language:	English
Published:	MDPI AG 2020-08-01
Series:	Biomolecules
Subjects:	galectin non-classical secretion endosome exosome sorting
Online Access:	https://www.mdpi.com/2218-273X/10/9/1232

id	doaj-1de25a426f924f06b76620b00ac9c372
record_format	Article
spelling	doaj-1de25a426f924f06b76620b00ac9c3722020-11-25T03:02:11ZengMDPI AGBiomolecules2218-273X2020-08-01101232123210.3390/biom10091232Galectins in Intra- and Extracellular VesiclesSebastian Bänfer0Ralf Jacob1Department of Cell Biology and Cell Pathology, Philipps-Universität Marburg, 35043 Marburg, GermanyDepartment of Cell Biology and Cell Pathology, Philipps-Universität Marburg, 35043 Marburg, GermanyCarbohydrate-binding galectins are expressed in various tissues of multicellular organisms. They are involved in autophagy, cell migration, immune response, inflammation, intracellular transport, and signaling. In recent years, novel roles of galectin-interaction with membrane components have been characterized, which lead to the formation of vesicles with diverse functions. These vesicles are part of intracellular transport pathways, belong to the cellular degradation machinery, or can be released for cell-to-cell communication. Several characteristics of galectins in the lumen or at the membrane of newly formed vesicular structures are discussed in this review and illustrate the need to fully elucidate their contributions at the molecular and structural level.https://www.mdpi.com/2218-273X/10/9/1232galectinnon-classical secretionendosomeexosomesorting
collection	DOAJ
language	English
format	Article
sources	DOAJ
author	Sebastian Bänfer Ralf Jacob
spellingShingle	Sebastian Bänfer Ralf Jacob Galectins in Intra- and Extracellular Vesicles Biomolecules galectin non-classical secretion endosome exosome sorting
author_facet	Sebastian Bänfer Ralf Jacob
author_sort	Sebastian Bänfer
title	Galectins in Intra- and Extracellular Vesicles
title_short	Galectins in Intra- and Extracellular Vesicles
title_full	Galectins in Intra- and Extracellular Vesicles
title_fullStr	Galectins in Intra- and Extracellular Vesicles
title_full_unstemmed	Galectins in Intra- and Extracellular Vesicles
title_sort	galectins in intra- and extracellular vesicles
publisher	MDPI AG
series	Biomolecules
issn	2218-273X
publishDate	2020-08-01
description	Carbohydrate-binding galectins are expressed in various tissues of multicellular organisms. They are involved in autophagy, cell migration, immune response, inflammation, intracellular transport, and signaling. In recent years, novel roles of galectin-interaction with membrane components have been characterized, which lead to the formation of vesicles with diverse functions. These vesicles are part of intracellular transport pathways, belong to the cellular degradation machinery, or can be released for cell-to-cell communication. Several characteristics of galectins in the lumen or at the membrane of newly formed vesicular structures are discussed in this review and illustrate the need to fully elucidate their contributions at the molecular and structural level.
topic	galectin non-classical secretion endosome exosome sorting
url	https://www.mdpi.com/2218-273X/10/9/1232
work_keys_str_mv	AT sebastianbanfer galectinsinintraandextracellularvesicles AT ralfjacob galectinsinintraandextracellularvesicles
_version_	1724690939505541120

Galectins in Intra- and Extracellular Vesicles

Similar Items