c-Myb regulates matrix metalloproteinases 1/9, and cathepsin D: implications for matrix-dependent breast cancer cell invasion and metastasis

c-Myb regulates matrix metalloproteinases 1/9, and cathepsin D: implications for matrix-dependent breast cancer cell invasion and metastasis

<p>Abstract</p> <p>Background</p> <p>The c-Myb transcription factor is essential for the maintenance of stem-progenitor cells in bone marrow, colon epithelia, and neurogenic niches. c-Myb malfunction contributes to several types of malignancies including breast cancer....

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Bibliographic Details
Main Authors: Knopfová Lucia, Beneš Petr, Pekarčíková Lucie, Hermanová Markéta, Masařík Michal, Pernicová Zuzana, Souček Karel, Šmarda Jan
Format: Article
Language:English
Published: BMC 2012-03-01
Series:Molecular Cancer
Subjects:
c-Myb
Metastasis
Breast cancer
Matrix metalloproteinase
Cathepsin D
Extracellular matrix
Online Access:http://www.molecular-cancer.com/content/11/1/15

Internet

http://www.molecular-cancer.com/content/11/1/15

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