Anti-Infective, Anti-Inflammatory, and Immunomodulatory Properties of Breast Milk Factors for the Protection of Infants in the Pandemic From COVID-19

COVID-19 pandemic since the end of 2019 spreads worldwide, counting millions of victims. The viral invasion, systemic inflammation, and consequent organ failure are the gravest features of coronavirus disease 2019 (COVID-19), and they are associated with a high mortality rate. The aim of this study...

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Main Authors: Pasqua Anna Quitadamo, Laura Comegna, Pierpaolo Cristalli
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-03-01
Series:Frontiers in Public Health
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fpubh.2020.589736/full
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spelling doaj-1dd71e845f1846b5bfdb39d63553bde82021-03-02T04:54:12ZengFrontiers Media S.A.Frontiers in Public Health2296-25652021-03-01810.3389/fpubh.2020.589736589736Anti-Infective, Anti-Inflammatory, and Immunomodulatory Properties of Breast Milk Factors for the Protection of Infants in the Pandemic From COVID-19Pasqua Anna QuitadamoLaura ComegnaPierpaolo CristalliCOVID-19 pandemic since the end of 2019 spreads worldwide, counting millions of victims. The viral invasion, systemic inflammation, and consequent organ failure are the gravest features of coronavirus disease 2019 (COVID-19), and they are associated with a high mortality rate. The aim of this study is to evaluate the role of breast milk in the COVID-19 pandemic, analyzing its antiviral, anti-inflammatory, and immunoregulatory effects due to its bioactive components, so numerous and important for the protection of infants. The study tried to demonstrate that all the components of human milk are capable of performing functions on all the pathogenic events recognized and described in COVID-19 disease. Those human milk factors are well-tolerated and practically free of side effects, so breast milk should become a research topic to discover therapies even in this epidemic. In the first part, the mechanisms of protection and defense of the breast milk elements will be delineated; in the second section, it will describe the human milk effects in viral infections and it will be hypothesized how the known mechanisms could act in COVID infection.https://www.frontiersin.org/articles/10.3389/fpubh.2020.589736/fullantiviral activityfunctions human milk factorsCOVID 19clinical application of human milk factorshuman milk research
collection DOAJ
language English
format Article
sources DOAJ
author Pasqua Anna Quitadamo
Laura Comegna
Pierpaolo Cristalli
spellingShingle Pasqua Anna Quitadamo
Laura Comegna
Pierpaolo Cristalli
Anti-Infective, Anti-Inflammatory, and Immunomodulatory Properties of Breast Milk Factors for the Protection of Infants in the Pandemic From COVID-19
Frontiers in Public Health
antiviral activity
functions human milk factors
COVID 19
clinical application of human milk factors
human milk research
author_facet Pasqua Anna Quitadamo
Laura Comegna
Pierpaolo Cristalli
author_sort Pasqua Anna Quitadamo
title Anti-Infective, Anti-Inflammatory, and Immunomodulatory Properties of Breast Milk Factors for the Protection of Infants in the Pandemic From COVID-19
title_short Anti-Infective, Anti-Inflammatory, and Immunomodulatory Properties of Breast Milk Factors for the Protection of Infants in the Pandemic From COVID-19
title_full Anti-Infective, Anti-Inflammatory, and Immunomodulatory Properties of Breast Milk Factors for the Protection of Infants in the Pandemic From COVID-19
title_fullStr Anti-Infective, Anti-Inflammatory, and Immunomodulatory Properties of Breast Milk Factors for the Protection of Infants in the Pandemic From COVID-19
title_full_unstemmed Anti-Infective, Anti-Inflammatory, and Immunomodulatory Properties of Breast Milk Factors for the Protection of Infants in the Pandemic From COVID-19
title_sort anti-infective, anti-inflammatory, and immunomodulatory properties of breast milk factors for the protection of infants in the pandemic from covid-19
publisher Frontiers Media S.A.
series Frontiers in Public Health
issn 2296-2565
publishDate 2021-03-01
description COVID-19 pandemic since the end of 2019 spreads worldwide, counting millions of victims. The viral invasion, systemic inflammation, and consequent organ failure are the gravest features of coronavirus disease 2019 (COVID-19), and they are associated with a high mortality rate. The aim of this study is to evaluate the role of breast milk in the COVID-19 pandemic, analyzing its antiviral, anti-inflammatory, and immunoregulatory effects due to its bioactive components, so numerous and important for the protection of infants. The study tried to demonstrate that all the components of human milk are capable of performing functions on all the pathogenic events recognized and described in COVID-19 disease. Those human milk factors are well-tolerated and practically free of side effects, so breast milk should become a research topic to discover therapies even in this epidemic. In the first part, the mechanisms of protection and defense of the breast milk elements will be delineated; in the second section, it will describe the human milk effects in viral infections and it will be hypothesized how the known mechanisms could act in COVID infection.
topic antiviral activity
functions human milk factors
COVID 19
clinical application of human milk factors
human milk research
url https://www.frontiersin.org/articles/10.3389/fpubh.2020.589736/full
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