Adaptive laboratory evolution of native methanol assimilation in Saccharomyces cerevisiae

Methylotrophic metabolism enables growth on methanol, an alternative to sugar fermentation. Here the authors use adaptive laboratory evolution to uncover native methylotrophy capacity in Saccharomyces cerevisiae.

Bibliographic Details
Main Authors: Monica I. Espinosa, Ricardo A. Gonzalez-Garcia, Kaspar Valgepea, Manuel R. Plan, Colin Scott, Isak S. Pretorius, Esteban Marcellin, Ian T. Paulsen, Thomas C. Williams
Format: Article
Language:English
Published: Nature Publishing Group 2020-11-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-020-19390-9
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spelling doaj-1dcbdbecd52142a095554b4b3fa339392021-05-11T08:46:32ZengNature Publishing GroupNature Communications2041-17232020-11-0111111210.1038/s41467-020-19390-9Adaptive laboratory evolution of native methanol assimilation in Saccharomyces cerevisiaeMonica I. Espinosa0Ricardo A. Gonzalez-Garcia1Kaspar Valgepea2Manuel R. Plan3Colin Scott4Isak S. Pretorius5Esteban Marcellin6Ian T. Paulsen7Thomas C. Williams8Department of Molecular Sciences, ARC Centre of Excellence in Synthetic Biology, Macquarie UniversityAustralian Institute for Bioengineering and Nanotechnology, The University of QueenslandAustralian Institute for Bioengineering and Nanotechnology, The University of QueenslandAustralian Institute for Bioengineering and Nanotechnology, The University of QueenslandCSIRO Synthetic Biology Future Science PlatformDepartment of Molecular Sciences, ARC Centre of Excellence in Synthetic Biology, Macquarie UniversityAustralian Institute for Bioengineering and Nanotechnology, The University of QueenslandDepartment of Molecular Sciences, ARC Centre of Excellence in Synthetic Biology, Macquarie UniversityDepartment of Molecular Sciences, ARC Centre of Excellence in Synthetic Biology, Macquarie UniversityMethylotrophic metabolism enables growth on methanol, an alternative to sugar fermentation. Here the authors use adaptive laboratory evolution to uncover native methylotrophy capacity in Saccharomyces cerevisiae.https://doi.org/10.1038/s41467-020-19390-9
collection DOAJ
language English
format Article
sources DOAJ
author Monica I. Espinosa
Ricardo A. Gonzalez-Garcia
Kaspar Valgepea
Manuel R. Plan
Colin Scott
Isak S. Pretorius
Esteban Marcellin
Ian T. Paulsen
Thomas C. Williams
spellingShingle Monica I. Espinosa
Ricardo A. Gonzalez-Garcia
Kaspar Valgepea
Manuel R. Plan
Colin Scott
Isak S. Pretorius
Esteban Marcellin
Ian T. Paulsen
Thomas C. Williams
Adaptive laboratory evolution of native methanol assimilation in Saccharomyces cerevisiae
Nature Communications
author_facet Monica I. Espinosa
Ricardo A. Gonzalez-Garcia
Kaspar Valgepea
Manuel R. Plan
Colin Scott
Isak S. Pretorius
Esteban Marcellin
Ian T. Paulsen
Thomas C. Williams
author_sort Monica I. Espinosa
title Adaptive laboratory evolution of native methanol assimilation in Saccharomyces cerevisiae
title_short Adaptive laboratory evolution of native methanol assimilation in Saccharomyces cerevisiae
title_full Adaptive laboratory evolution of native methanol assimilation in Saccharomyces cerevisiae
title_fullStr Adaptive laboratory evolution of native methanol assimilation in Saccharomyces cerevisiae
title_full_unstemmed Adaptive laboratory evolution of native methanol assimilation in Saccharomyces cerevisiae
title_sort adaptive laboratory evolution of native methanol assimilation in saccharomyces cerevisiae
publisher Nature Publishing Group
series Nature Communications
issn 2041-1723
publishDate 2020-11-01
description Methylotrophic metabolism enables growth on methanol, an alternative to sugar fermentation. Here the authors use adaptive laboratory evolution to uncover native methylotrophy capacity in Saccharomyces cerevisiae.
url https://doi.org/10.1038/s41467-020-19390-9
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