Investigation of Polyaniline and a Functionalised Derivative as Antimicrobial Additives to Create Contamination Resistant Surfaces

Antimicrobial surfaces can be applied to break transmission pathways in hospitals. Polyaniline (PANI) and poly(3-aminobenzoic acid) (P3ABA) are novel antimicrobial agents with potential as non-leaching additives to provide contamination resistant surfaces. The activity of PANI and P3ABA were investi...

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Main Authors: Julia Robertson, Marija Gizdavic-Nikolaidis, Simon Swift
Format: Article
Language:English
Published: MDPI AG 2018-03-01
Series:Materials
Subjects:
Online Access:http://www.mdpi.com/1996-1944/11/3/436
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spelling doaj-1dca67e004cd482880fb9951445208452020-11-24T22:45:18ZengMDPI AGMaterials1996-19442018-03-0111343610.3390/ma11030436ma11030436Investigation of Polyaniline and a Functionalised Derivative as Antimicrobial Additives to Create Contamination Resistant SurfacesJulia Robertson0Marija Gizdavic-Nikolaidis1Simon Swift2Department of Molecular Medicine and Pathology, The University of Auckland, Auckland 1023, New ZealandSchool of Chemical Sciences, The University of Auckland, Auckland 1142, New ZealandDepartment of Molecular Medicine and Pathology, The University of Auckland, Auckland 1023, New ZealandAntimicrobial surfaces can be applied to break transmission pathways in hospitals. Polyaniline (PANI) and poly(3-aminobenzoic acid) (P3ABA) are novel antimicrobial agents with potential as non-leaching additives to provide contamination resistant surfaces. The activity of PANI and P3ABA were investigated in suspension and as part of absorbent and non-absorbent surfaces. The effect of inoculum size and the presence of organic matter on surface activity was determined. PANI and P3ABA both demonstrated bactericidal activity against Escherichia coli and Staphylococcus aureus in suspension and as part of an absorbent surface. Only P3ABA showed antimicrobial activity in non-absorbent films. The results that are presented in this work support the use of P3ABA to create contamination resistant surfaces.http://www.mdpi.com/1996-1944/11/3/436antimicrobialsurfacesinfection controlpolyanilineEscherichia coliStaphylococcus aureus
collection DOAJ
language English
format Article
sources DOAJ
author Julia Robertson
Marija Gizdavic-Nikolaidis
Simon Swift
spellingShingle Julia Robertson
Marija Gizdavic-Nikolaidis
Simon Swift
Investigation of Polyaniline and a Functionalised Derivative as Antimicrobial Additives to Create Contamination Resistant Surfaces
Materials
antimicrobial
surfaces
infection control
polyaniline
Escherichia coli
Staphylococcus aureus
author_facet Julia Robertson
Marija Gizdavic-Nikolaidis
Simon Swift
author_sort Julia Robertson
title Investigation of Polyaniline and a Functionalised Derivative as Antimicrobial Additives to Create Contamination Resistant Surfaces
title_short Investigation of Polyaniline and a Functionalised Derivative as Antimicrobial Additives to Create Contamination Resistant Surfaces
title_full Investigation of Polyaniline and a Functionalised Derivative as Antimicrobial Additives to Create Contamination Resistant Surfaces
title_fullStr Investigation of Polyaniline and a Functionalised Derivative as Antimicrobial Additives to Create Contamination Resistant Surfaces
title_full_unstemmed Investigation of Polyaniline and a Functionalised Derivative as Antimicrobial Additives to Create Contamination Resistant Surfaces
title_sort investigation of polyaniline and a functionalised derivative as antimicrobial additives to create contamination resistant surfaces
publisher MDPI AG
series Materials
issn 1996-1944
publishDate 2018-03-01
description Antimicrobial surfaces can be applied to break transmission pathways in hospitals. Polyaniline (PANI) and poly(3-aminobenzoic acid) (P3ABA) are novel antimicrobial agents with potential as non-leaching additives to provide contamination resistant surfaces. The activity of PANI and P3ABA were investigated in suspension and as part of absorbent and non-absorbent surfaces. The effect of inoculum size and the presence of organic matter on surface activity was determined. PANI and P3ABA both demonstrated bactericidal activity against Escherichia coli and Staphylococcus aureus in suspension and as part of an absorbent surface. Only P3ABA showed antimicrobial activity in non-absorbent films. The results that are presented in this work support the use of P3ABA to create contamination resistant surfaces.
topic antimicrobial
surfaces
infection control
polyaniline
Escherichia coli
Staphylococcus aureus
url http://www.mdpi.com/1996-1944/11/3/436
work_keys_str_mv AT juliarobertson investigationofpolyanilineandafunctionalisedderivativeasantimicrobialadditivestocreatecontaminationresistantsurfaces
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AT simonswift investigationofpolyanilineandafunctionalisedderivativeasantimicrobialadditivestocreatecontaminationresistantsurfaces
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