CHARTS: a web application for characterizing and comparing tumor subpopulations in publicly available single-cell RNA-seq data sets

Abstract Background Single-cell RNA-seq (scRNA-seq) enables the profiling of genome-wide gene expression at the single-cell level and in so doing facilitates insight into and information about cellular heterogeneity within a tissue. This is especially important in cancer, where tumor and tumor micro...

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Bibliographic Details
Main Authors: Matthew N. Bernstein, Zijian Ni, Michael Collins, Mark E. Burkard, Christina Kendziorski, Ron Stewart
Format: Article
Language:English
Published: BMC 2021-02-01
Series:BMC Bioinformatics
Online Access:https://doi.org/10.1186/s12859-021-04021-x