Synthetic α-Conotoxin Mutants as Probes for Studying Nicotinic Acetylcholine Receptors and in the Development of Novel Drug Leads
α-Conotoxins are peptide neurotoxins isolated from venomous marine cone snails that are potent and selective antagonists for different subtypes of nicotinic acetylcholine receptors (nAChRs). As such, they are valuable probes for dissecting the role that nAChRs play in nervous system function. In rec...
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| Format: | Article |
| Language: | English |
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MDPI AG
2010-06-01
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| Series: | Toxins |
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| Online Access: | http://www.mdpi.com/2072-6651/2/6/1471/ |