Arterial Hypertension and Tyrosine Kinase Inhibitors in Chronic Myeloid Leukemia: A Systematic Review and Meta-Analysis

Arterial Hypertension and Tyrosine Kinase Inhibitors in Chronic Myeloid Leukemia: A Systematic Review and Meta-Analysis

Background: Off-target effects in chronic myeloid leukemia (CML) patients treated with tyrosine kinase inhibitors (TKIs) are associated with cardiovascular toxicity. Hypertension represents an important cardiovascular complication and, if not appropriately managed, can contribute to developing throm...

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Bibliographic Details
Main Authors: Olga Mulas, Giovanni Caocci, Brunella Mola, Giorgio La Nasa
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-09-01
Series:Frontiers in Pharmacology
Subjects:
chronic myeloid
leukemia
tyrosine kinase inhibitor
hypertension
cardiovascular
Online Access:https://www.frontiersin.org/articles/10.3389/fphar.2021.674748/full

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