Can Homeopathy Bring Additional Benefits to Thalassemic Patients on Hydroxyurea Therapy? Encouraging Results of a Preliminary Study

Several homeopathic remedies, namely, Pulsatilla Nigricans (30th potency), Ceanothus Americanus (both mother tincture and 6th potency) and Ferrum Metallicum (30th potency) selected as per similia principles were administered to 38 thalassemic patients receiving Hydroxyurea (HU) therapy for a varying...

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Main Authors: Antara Banerjee, Sudipa Basu Chakrabarty, Susanta Roy Karmakar, Amit Chakrabarty, Surjyo Jyoti Biswas, Saiful Haque, Debarsi Das, Saili Paul, Biswapati Mandal, Boujedaini Naoual, Philippe Belon, Anisur Rahman Khuda-Bukhsh
Format: Article
Language:English
Published: Hindawi Limited 2010-01-01
Series:Evidence-Based Complementary and Alternative Medicine
Online Access:http://dx.doi.org/10.1093/ecam/nem161
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spelling doaj-1d8f63e150c44ca4a821283825ba42d72020-11-24T23:47:32ZengHindawi LimitedEvidence-Based Complementary and Alternative Medicine1741-427X1741-42882010-01-017112913610.1093/ecam/nem161Can Homeopathy Bring Additional Benefits to Thalassemic Patients on Hydroxyurea Therapy? Encouraging Results of a Preliminary StudyAntara Banerjee0Sudipa Basu Chakrabarty1Susanta Roy Karmakar2Amit Chakrabarty3Surjyo Jyoti Biswas4Saiful Haque5Debarsi Das6Saili Paul7Biswapati Mandal8Boujedaini Naoual9Philippe Belon10Anisur Rahman Khuda-Bukhsh11Cytogenetics and Molecular Biology Laboratory, Department of Zoology, University of Kalyani, Kalyani-741 235, West Bengal, IndiaInstitute of Genetic Engineering, 30 Thakurhat Road, Badu, Kolkata-700 128, IndiaCytogenetics and Molecular Biology Laboratory, Department of Zoology, University of Kalyani, Kalyani-741 235, West Bengal, IndiaInstitute of Genetic Engineering, 30 Thakurhat Road, Badu, Kolkata-700 128, IndiaCytogenetics and Molecular Biology Laboratory, Department of Zoology, University of Kalyani, Kalyani-741 235, West Bengal, IndiaCytogenetics and Molecular Biology Laboratory, Department of Zoology, University of Kalyani, Kalyani-741 235, West Bengal, IndiaCytogenetics and Molecular Biology Laboratory, Department of Zoology, University of Kalyani, Kalyani-741 235, West Bengal, IndiaCytogenetics and Molecular Biology Laboratory, Department of Zoology, University of Kalyani, Kalyani-741 235, West Bengal, IndiaDirectorate of Research, Bidhan Chandra Krishi Viswavidyalaya, Kalyani, West Bengal, IndiaBoiron Laboratory, 20 Rue de la Liberation, Sainte-Foy-Les-Lyon, FranceBoiron Laboratory, 20 Rue de la Liberation, Sainte-Foy-Les-Lyon, FranceCytogenetics and Molecular Biology Laboratory, Department of Zoology, University of Kalyani, Kalyani-741 235, West Bengal, IndiaSeveral homeopathic remedies, namely, Pulsatilla Nigricans (30th potency), Ceanothus Americanus (both mother tincture and 6th potency) and Ferrum Metallicum (30th potency) selected as per similia principles were administered to 38 thalassemic patients receiving Hydroxyurea (HU) therapy for a varying period of time. Levels of serum ferritin (SF), fetal hemoglobin (HbF), hemoglobin (Hb), platelet count (PC), mean corpuscular volume (MCV), mean corpuscular hemoglobin concentration (MCHC), mean corpuscular hemoglobin (MCH), white blood cell (WBC) count, bilirubin content, alanine amino transferase (ALT), aspartate amino transferase (AST) and serum total protein content of patients were determined before and 3 months after administration of the homeopathic remedies in combination with HU to evaluate additional benefits, if any, derived by the homeopathic remedies, by comparing the data with those of 38 subjects receiving only HU therapy. Preliminary results indicated that there was a significant decrease in the SF and increase in HbF levels in the combined, treated subjects. Although the changes in other parameters were not so significant, there was a significant decrease in size of spleen in most patients with spleenomegaly and improvement in general health conditions along with an increased gap between transfusions in most patients receiving the combined homeopathic treatment. The homeopathic remedies being inexpensive and without any known side-effects seem to have great potentials in bringing additional benefits to thalassemic patients; particularly in the developing world where blood transfusions suffer from inadequate screening and fall short of the stringent safety standards followed in the developed countries. Further independent studies are encouraged.http://dx.doi.org/10.1093/ecam/nem161
collection DOAJ
language English
format Article
sources DOAJ
author Antara Banerjee
Sudipa Basu Chakrabarty
Susanta Roy Karmakar
Amit Chakrabarty
Surjyo Jyoti Biswas
Saiful Haque
Debarsi Das
Saili Paul
Biswapati Mandal
Boujedaini Naoual
Philippe Belon
Anisur Rahman Khuda-Bukhsh
spellingShingle Antara Banerjee
Sudipa Basu Chakrabarty
Susanta Roy Karmakar
Amit Chakrabarty
Surjyo Jyoti Biswas
Saiful Haque
Debarsi Das
Saili Paul
Biswapati Mandal
Boujedaini Naoual
Philippe Belon
Anisur Rahman Khuda-Bukhsh
Can Homeopathy Bring Additional Benefits to Thalassemic Patients on Hydroxyurea Therapy? Encouraging Results of a Preliminary Study
Evidence-Based Complementary and Alternative Medicine
author_facet Antara Banerjee
Sudipa Basu Chakrabarty
Susanta Roy Karmakar
Amit Chakrabarty
Surjyo Jyoti Biswas
Saiful Haque
Debarsi Das
Saili Paul
Biswapati Mandal
Boujedaini Naoual
Philippe Belon
Anisur Rahman Khuda-Bukhsh
author_sort Antara Banerjee
title Can Homeopathy Bring Additional Benefits to Thalassemic Patients on Hydroxyurea Therapy? Encouraging Results of a Preliminary Study
title_short Can Homeopathy Bring Additional Benefits to Thalassemic Patients on Hydroxyurea Therapy? Encouraging Results of a Preliminary Study
title_full Can Homeopathy Bring Additional Benefits to Thalassemic Patients on Hydroxyurea Therapy? Encouraging Results of a Preliminary Study
title_fullStr Can Homeopathy Bring Additional Benefits to Thalassemic Patients on Hydroxyurea Therapy? Encouraging Results of a Preliminary Study
title_full_unstemmed Can Homeopathy Bring Additional Benefits to Thalassemic Patients on Hydroxyurea Therapy? Encouraging Results of a Preliminary Study
title_sort can homeopathy bring additional benefits to thalassemic patients on hydroxyurea therapy? encouraging results of a preliminary study
publisher Hindawi Limited
series Evidence-Based Complementary and Alternative Medicine
issn 1741-427X
1741-4288
publishDate 2010-01-01
description Several homeopathic remedies, namely, Pulsatilla Nigricans (30th potency), Ceanothus Americanus (both mother tincture and 6th potency) and Ferrum Metallicum (30th potency) selected as per similia principles were administered to 38 thalassemic patients receiving Hydroxyurea (HU) therapy for a varying period of time. Levels of serum ferritin (SF), fetal hemoglobin (HbF), hemoglobin (Hb), platelet count (PC), mean corpuscular volume (MCV), mean corpuscular hemoglobin concentration (MCHC), mean corpuscular hemoglobin (MCH), white blood cell (WBC) count, bilirubin content, alanine amino transferase (ALT), aspartate amino transferase (AST) and serum total protein content of patients were determined before and 3 months after administration of the homeopathic remedies in combination with HU to evaluate additional benefits, if any, derived by the homeopathic remedies, by comparing the data with those of 38 subjects receiving only HU therapy. Preliminary results indicated that there was a significant decrease in the SF and increase in HbF levels in the combined, treated subjects. Although the changes in other parameters were not so significant, there was a significant decrease in size of spleen in most patients with spleenomegaly and improvement in general health conditions along with an increased gap between transfusions in most patients receiving the combined homeopathic treatment. The homeopathic remedies being inexpensive and without any known side-effects seem to have great potentials in bringing additional benefits to thalassemic patients; particularly in the developing world where blood transfusions suffer from inadequate screening and fall short of the stringent safety standards followed in the developed countries. Further independent studies are encouraged.
url http://dx.doi.org/10.1093/ecam/nem161
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