Evolving management of positive regional lymph nodes in melanoma: Past, present and future directions
Sentinel lymph node (SLN) biopsy has become the standard of care for lymph node staging in melanoma and the most important predictor of survival in clinically node-negative disease. Previous guidelines recommend completion lymph node dissection (CLND) in cases of positive SLN; however, the lymph no...
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PAGEPress Publications
2019-11-01
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| Series: | Oncology Reviews |
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| Online Access: | https://www.oncologyreviews.org/index.php/or/article/view/433 |
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doaj-1d8f048e20674909837622b299498f3b2020-11-25T03:19:38ZengPAGEPress PublicationsOncology Reviews1970-55571970-55652019-11-0113210.4081/oncol.2019.433Evolving management of positive regional lymph nodes in melanoma: Past, present and future directionsRachel A. Fayne0Francisco I. Macedo1Steven E. Rodgers2Mecker G. Möller3Division of Surgical Oncology, Dewitt-Daughtry Department of Surgery, Sylvester Comprehensive Cancer Center, University of Miami Miller School of Medicine, Miami, FLDepartment of Surgery, North Florida Regional Medical Center, University of Central Florida College of Medicine, Miami, FLDivision of Surgical Oncology, Dewitt-Daughtry Department of Surgery, Sylvester Comprehensive Cancer Center, University of Miami Miller School of Medicine, Miami, FLDivision of Surgical Oncology, Dewitt-Daughtry Department of Surgery, Sylvester Comprehensive Cancer Center, University of Miami Miller School of Medicine, Miami, FL Sentinel lymph node (SLN) biopsy has become the standard of care for lymph node staging in melanoma and the most important predictor of survival in clinically node-negative disease. Previous guidelines recommend completion lymph node dissection (CLND) in cases of positive SLN; however, the lymph nodes recovered during CLND are only positive in a minority of these cases. Recent evidence suggests that conservative management (i.e. observation) has similar outcomes compared to CLND. We sought to review the most current literature regarding the management of SLN in metastatic melanoma and to discuss potential future directions. https://www.oncologyreviews.org/index.php/or/article/view/433Melanomasentinel lymph node biopsycompletion lymph node dissection. |
| collection |
DOAJ |
| language |
English |
| format |
Article |
| sources |
DOAJ |
| author |
Rachel A. Fayne Francisco I. Macedo Steven E. Rodgers Mecker G. Möller |
| spellingShingle |
Rachel A. Fayne Francisco I. Macedo Steven E. Rodgers Mecker G. Möller Evolving management of positive regional lymph nodes in melanoma: Past, present and future directions Oncology Reviews Melanoma sentinel lymph node biopsy completion lymph node dissection. |
| author_facet |
Rachel A. Fayne Francisco I. Macedo Steven E. Rodgers Mecker G. Möller |
| author_sort |
Rachel A. Fayne |
| title |
Evolving management of positive regional lymph nodes in melanoma: Past, present and future directions |
| title_short |
Evolving management of positive regional lymph nodes in melanoma: Past, present and future directions |
| title_full |
Evolving management of positive regional lymph nodes in melanoma: Past, present and future directions |
| title_fullStr |
Evolving management of positive regional lymph nodes in melanoma: Past, present and future directions |
| title_full_unstemmed |
Evolving management of positive regional lymph nodes in melanoma: Past, present and future directions |
| title_sort |
evolving management of positive regional lymph nodes in melanoma: past, present and future directions |
| publisher |
PAGEPress Publications |
| series |
Oncology Reviews |
| issn |
1970-5557 1970-5565 |
| publishDate |
2019-11-01 |
| description |
Sentinel lymph node (SLN) biopsy has become the standard of care for lymph node staging in melanoma and the most important predictor of survival in clinically node-negative disease. Previous guidelines recommend completion lymph node dissection (CLND) in cases of positive SLN; however, the lymph nodes recovered during CLND are only positive in a minority of these cases. Recent evidence suggests that conservative management (i.e. observation) has similar outcomes compared to CLND. We sought to review the most current literature regarding the management of SLN in metastatic melanoma and to discuss potential future directions.
|
| topic |
Melanoma sentinel lymph node biopsy completion lymph node dissection. |
| url |
https://www.oncologyreviews.org/index.php/or/article/view/433 |
| work_keys_str_mv |
AT rachelafayne evolvingmanagementofpositiveregionallymphnodesinmelanomapastpresentandfuturedirections AT franciscoimacedo evolvingmanagementofpositiveregionallymphnodesinmelanomapastpresentandfuturedirections AT stevenerodgers evolvingmanagementofpositiveregionallymphnodesinmelanomapastpresentandfuturedirections AT meckergmoller evolvingmanagementofpositiveregionallymphnodesinmelanomapastpresentandfuturedirections |
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1724621136214360064 |