The Flavonol Isoquercitrin Promotes Mitochondrial-Dependent Apoptosis in SK-Mel-2 Melanoma Cell via the PI3K/AKT/mTOR Pathway

The Flavonol Isoquercitrin Promotes Mitochondrial-Dependent Apoptosis in SK-Mel-2 Melanoma Cell via the PI3K/AKT/mTOR Pathway

Isoquercitrin (IQ), a major flavonol present in <i>Prunus mume</i> fruit, has gained much attention in recent studies because of its superior bioavailability and physiological effects. In this study, the anti-cancer mechanism of IQ against human melanoma, particularly its effect on the m...

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Bibliographic Details
Main Authors: Yeong-Seon Won, Jeong-Ho Kim, Rona Camille M. Lizardo, Hye-Ji Min, Hyun-Dong Cho, Seong-Min Hong, Kwon-Il Seo
Format: Article
Language:English
Published: MDPI AG 2020-11-01
Series:Nutrients
Subjects:
isoquercitrin
flavonol
human melanoma
mitochondrial-mediated apoptosis
natural chemopreventive agent
Online Access:https://www.mdpi.com/2072-6643/12/12/3683

Internet

https://www.mdpi.com/2072-6643/12/12/3683

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