PEGylated gold nanoparticles-ribonuclease induced oxidative stress and apoptosis in colorectal cancer cells

PEGylated gold nanoparticles-ribonuclease induced oxidative stress and apoptosis in colorectal cancer cells

Introduction: Currently, drug-induced reactive oxygen species (ROS) mediating apoptosis pathway have extensively been investigated in designing effective strategies for colorectal cancer (CRC) chemotherapy. Bovine pancreatic ribonuclease A (RNase A) represents a new class of cytotoxic and non-mutage...

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Bibliographic Details
Main Authors: Mostafa Akbarzadeh Khiavi, Azam Safary, Jaleh Barar, Hamed Farzi-Khajeh, Abolfazl Barzegari, Rahimeh Mousavi, Mohammad Hossein Somi, Yadollah Omidi
Format: Article
Language:English
Published: Tabriz University of Medical Sciences 2020-01-01
Series:BioImpacts
Subjects:
bovine pancreatic ribonuclease
colorectal cancer
gold nanoparticles
nanomedicine
pegylation
reactive oxygen species
Online Access:https://bi.tbzmed.ac.ir/PDF/bi-10-27.pdf

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