Plant Volatile, Phenylacetaldehyde Targets Breast Cancer Stem Cell by Induction of ROS and Regulation of Stat3 Signal

Cancer stem cells (CSCs) are undifferentiated cells that give rise to tumor and resistance to chemotherapy. This study reports that phenylacetaldehyde (PAA), a flower flavor, inhibits formation on breast CSCs. PAA showed anti-proliferation and increased apoptosis of breast cancer. PAA also reduced t...

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Bibliographic Details
Main Authors: Hack Sun Choi, Su-Lim Kim, Ji-Hyang Kim, Yu-Chan Ko, Dong-Sun Lee
Format: Article
Language:English
Published: MDPI AG 2020-11-01
Series:Antioxidants
Subjects:
ROS
Online Access:https://www.mdpi.com/2076-3921/9/11/1119