A Novel Flow-Perfusion Bioreactor Supports 3D Dynamic Cell Culture

Background. Bone engineering requires thicker three-dimensional constructs than the maximum thickness supported by standard cell-culture techniques (2 mm). A flow-perfusion bioreactor was developed to provide chemotransportation to thick (6 mm) scaffolds. Methods. Polyurethane scaffolds, seeded wit...

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Bibliographic Details
Main Authors: Alexander M. Sailon, Alexander C. Allori, Edward H. Davidson, Derek D. Reformat, Robert J. Allen, Stephen M. Warren
Format: Article
Language:English
Published: Hindawi Limited 2009-01-01
Series:Journal of Biomedicine and Biotechnology
Online Access:http://dx.doi.org/10.1155/2009/873816